Comparing liver transplant methods for colorectal cancer patients
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study
This study is testing different liver transplant methods for colorectal cancer patients to see which one helps them recover faster and live longer after the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Northwestern University Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06698146 on ClinicalTrials.gov |
What this trial studies
This study examines the clinical outcomes of various liver transplant methods for patients with unresectable liver metastases from colorectal cancer. It compares living versus deceased donor transplants, whole organ versus split liver transplants, and one-stage versus two-stage procedures. The study will assess factors such as hospital recovery times and one-year survival rates post-transplant. Additionally, blood samples will be collected for future research purposes. All methods being evaluated are standard practices approved by the United Network of Organ Sharing.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are listed for liver transplantation due to colorectal cancer metastases.
Not a fit: Patients who are unable to provide informed consent or have certain clinical or anatomical issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment options and outcomes for patients with colorectal cancer that has spread to the liver.
How similar studies have performed: Other studies have shown success with various liver transplant methods, making this approach a continuation of established practices.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion: 1. All Patients of either gender ≥ 18 years of age who are listed for Liver transplant candidates at Northwestern with liver metastases due to colorectal cancer (CRLM). 2. Subjects must be able to provide informed consent themselves and without the use of a legally authorized representative (LAR), to be determined by the PI or Sub-I at the time of Consent. Exclusion: 1. Adults unable to consent 2. Pregnant Women 3. Certain clinical/surgical/anatomical parameters, at the discretion of the PI.
Where this trial is running
Chicago, Illinois
- Northwestern University-Comprehensive Transplant Center — Chicago, Illinois, United States (Recruiting)
Study contacts
- Study coordinator: Yajaira Navarro
- Email: a-daud@northwestern.edu
- Phone: 312-694-2092
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.