Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing liver transplant methods for colorectal cancer patients

Official title: Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study

Run by Northwestern University · NCT06698146 · Data updated 2026-11-12

This study is testing different liver transplant methods for colorectal cancer patients to see which one helps them recover faster and live longer after the surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment80 (estimated)
SponsorNorthwestern University
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedAugust 27, 2025
Main results expectedJanuary 1, 2034
Study endsJanuary 1, 2035
Registry record updatedJuly 10, 2026
Trial IDNCT06698146 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are listed for liver transplantation due to colorectal cancer metastases.

Probably not a fit

Patients who are unable to provide informed consent or have certain clinical or anatomical issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the clinical outcomes of various liver transplant methods for patients with unresectable liver metastases from colorectal cancer. It compares living versus deceased donor transplants, whole organ versus split liver transplants, and one-stage versus two-stage procedures. The study will assess factors such as hospital recovery times and one-year survival rates post-transplant. Additionally, blood samples will be collected for future research purposes. All methods being evaluated are standard practices approved by the United Network of Organ Sharing.

Why it matters

Potential benefit: If successful, this study could improve treatment options and outcomes for patients with colorectal cancer that has spread to the liver.

How similar studies have gone: Other studies have shown success with various liver transplant methods, making this approach a continuation of established practices.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion:

1. All Patients of either gender ≥ 18 years of age who are listed for Liver transplant candidates at Northwestern with liver metastases due to colorectal cancer (CRLM).
2. Subjects must be able to provide informed consent themselves and without the use of a legally authorized representative (LAR), to be determined by the PI or Sub-I at the time of Consent.

Exclusion:

1. Adults unable to consent
2. Pregnant Women
3. Certain clinical/surgical/anatomical parameters, at the discretion of the PI.

Where it's running

  • Northwestern University-Comprehensive Transplant Center
    Chicago, Illinois, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.