Comparing injections for treating rotator cuff tears
Official title: Comparison of Steroid, Platelet-rich Plasma and Platelet-rich Plasma Plus Hyaluronic Acid Injection for Rotator Cuff Lesions
Run by Kaohsiung Medical University · NCT06237647 · Data updated 2026-11-12
This study is testing three different injection treatments for shoulder pain from rotator cuff tears to see which one helps people feel better and recover faster.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 85 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Kaohsiung Medical University Academic / other |
| Locations | 1 site (Kaohsiung City, Sanmin) |
| Status | Recruiting |
| Started | February 17, 2023 |
| Main results expected | December 30, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | March 5, 2025 |
| Trial ID | NCT06237647 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 20 to 85 with shoulder pain lasting at least one month and a diagnosed partial-thickness rotator cuff tear.
✕Probably not a fit
Patients with inflammatory diseases, full-thickness tears, or a history of shoulder surgery are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of three different injection treatments for chronic rotator cuff partial tears: steroids, platelet-rich plasma (PRP), and a combination of PRP with hyaluronic acid (HA). The goal is to determine which treatment provides the best pain relief and functional recovery for patients suffering from shoulder pain. Participants will receive one injection of the selected treatment after undergoing a blood collection process to prepare the PRP. The study aims to provide insights into the synergistic effects of PRP and HA on tissue repair.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and recovery for patients with rotator cuff lesions.
How similar studies have gone: Other studies have shown promising results with PRP and HA injections for similar conditions, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * A. Shoulder pain for at least 1 months * B.partial-thickness tear diagnosed by MRI or Echo * C.age between 20 and 85 years old Exclusion Criteria: * A. inflammatory disease, such as rheumatoid arthritis, SLE, etc. * B. pregnancy * C. known malignancy * D. hematologic disease (or hemoglobin \<10 g/dl, platelet \<150.000 ul) * E. history of shoulder infection * F. history of shoulder surgery * G. prior steroid injection for 3 times or more * H. full-thickness tear * I. other shoulder problems, such as osteoarthritis, fracture malunion, etc. * J. subjects who cannot comply with the protocol of study * K. The shoulder pain area has been treated with PRP for less than 3 months
Where it's running
-
Kaohsiung Medical University Hospital
Kaohsiung City, Sanmin, Taiwan Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.