Clinical trial Recruiting at 1 site Interventional Ages 20 to 85

Comparing injections for treating rotator cuff tears

Official title: Comparison of Steroid, Platelet-rich Plasma and Platelet-rich Plasma Plus Hyaluronic Acid Injection for Rotator Cuff Lesions

Run by Kaohsiung Medical University · NCT06237647 · Data updated 2026-11-12

This study is testing three different injection treatments for shoulder pain from rotator cuff tears to see which one helps people feel better and recover faster.

Quick facts

Study typeInterventional
Ages20 Years to 85 Years
SexAll
Enrollment80 (estimated)
SponsorKaohsiung Medical University
Academic / other
Locations1 site (Kaohsiung City, Sanmin)
StatusRecruiting
StartedFebruary 17, 2023
Main results expectedDecember 30, 2027
Study endsDecember 31, 2027
Registry record updatedMarch 5, 2025
Trial IDNCT06237647 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 20 to 85 with shoulder pain lasting at least one month and a diagnosed partial-thickness rotator cuff tear.

Probably not a fit

Patients with inflammatory diseases, full-thickness tears, or a history of shoulder surgery are unlikely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of three different injection treatments for chronic rotator cuff partial tears: steroids, platelet-rich plasma (PRP), and a combination of PRP with hyaluronic acid (HA). The goal is to determine which treatment provides the best pain relief and functional recovery for patients suffering from shoulder pain. Participants will receive one injection of the selected treatment after undergoing a blood collection process to prepare the PRP. The study aims to provide insights into the synergistic effects of PRP and HA on tissue repair.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and recovery for patients with rotator cuff lesions.

How similar studies have gone: Other studies have shown promising results with PRP and HA injections for similar conditions, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* A. Shoulder pain for at least 1 months
* B.partial-thickness tear diagnosed by MRI or Echo
* C.age between 20 and 85 years old

Exclusion Criteria:

* A. inflammatory disease, such as rheumatoid arthritis, SLE, etc.
* B. pregnancy
* C. known malignancy
* D. hematologic disease (or hemoglobin \<10 g/dl, platelet \<150.000 ul)
* E. history of shoulder infection
* F. history of shoulder surgery
* G. prior steroid injection for 3 times or more
* H. full-thickness tear
* I. other shoulder problems, such as osteoarthritis, fracture malunion, etc.
* J. subjects who cannot comply with the protocol of study
* K. The shoulder pain area has been treated with PRP for less than 3 months

Where it's running

  • Kaohsiung Medical University Hospital
    Kaohsiung City, Sanmin, Taiwan
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.