Comparing indirect and direct pulp capping for deep caries in molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of indirect versus direct pulp capping techniques in treating deeply carious mandibular molars showing signs of moderate pulpitis. Participants will undergo either partial or complete caries removal followed by the respective pulp capping method. The study will assess both clinical and radiographic outcomes, as well as pain incidence and severity post-treatment. The goal is to determine which method provides better healing outcomes for the affected teeth.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The patient should be ≥18 years of age.
2. Restorable mature permanent 1st and 2nd Mandibular molars with deep caries (reaching inner quarter of dentine)
3. Tooth should give positive response to pulp sensibility testing.
4. Clinical diagnosis of moderate pulpitis.
5. Radiographic finding of periapical index (PAI) score ≤2.
6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).
7. Pulp exposure after complete caries excavation.
8. No pulp exposure after incomplete caries excavation

Exclusion Criteria:

1. Teeth with immature roots.
2. Pulp exposure after incomplete caries excavation.
3. No pulp exposure after complete caries excavation.
4. Bleeding could not be controlled in 5 minutes.
5. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.
6. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.
7. Internal/external resorption.
8. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)

Where it's running

• PGIDS, Rohtak
  Rohtak, Haryana, India Recruiting

Study contacts

• Study coordinator: Dr. Vinay Kumar, MDS
• Email: 29vinaykr@gmail.com
• Phone: 8901149107

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Direct pulp capping for deep and extremely deep caries in mature molars with reversible pulpitis

  This study tests whether direct pulp capping works similarly for deep versus extremely deep caries in adult, mature mandibular molars with reversible pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07696702

• Direct pulp capping in lower molars with side (proximal) versus top (occlusal) cavities: does the cavity location matter?

  This research will test whether direct pulp capping works as well for lower molars with side (proximal) cavities as for those with top (occlusal) cavities in people aged 15–40 who have reversible pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07578662

• Using pulpal blood biomarkers to predict success of vital pulp therapy in symptomatic teeth

  This trial will test whether measuring metabolic biomarkers in pulpal blood at the time of carious pulp exposure can help predict 12-month success of vital pulp treatment in people aged 16–50 with symptomatic deep caries.

  Recruiting University of Baghdad · Baghdad · NCT07452614

• Comparing a dental anesthesia injector versus the traditional syringe for numbing upper baby molars in children

  This trial tests whether a dental anesthesia injector causes less pain and anxiety than a regular syringe in 6–8-year-old children needing local anesthesia for pulpotomy.

  Recruiting at 2 sites Ain Shams University · Cairo, Cairo Governorate and 1 other locations · NCT07101068

• Evaluating the success of vital pulp therapy methods for dental pulp exposure

  This study is testing different ways to treat exposed dental pulp to see which methods work best for adults with teeth that can be saved.

  Recruiting Semmelweis University · Budapest · NCT06844448

• Egyptian MTA and Biodentine versus Calcium Hydroxide for indirect pulp capping in permanent teeth

  This will test whether Egyptian MTA or Biodentine work better than calcium hydroxide for indirect pulp capping in adults with deep cavities to help keep the tooth's pulp healthy.

  Recruiting Phase 4 Cairo University · Cairo · NCT06683833

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.