Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Comparing immediate and delayed dental implant placement outcomes

Official title: Esthetic, Clinical and Radiographic Outcomes of Immediate Implant Placement and Delayed Implant Placement in the Anterior Region of the Maxilla

Run by Sun Yat-sen University · NCT02814149 · Data updated 2026-11-12

This study is testing whether getting dental implants right after a tooth is removed works better than waiting a while, by looking at how well the gums and bone heal in both cases.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment40 (estimated)
SponsorSun Yat-sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedMay 2016
Main results expectedDecember 2026
Study endsJune 2027
Registry record updatedNovember 1, 2019
Trial IDNCT02814149 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are missing a single tooth in the maxillary anterior region and have adjacent natural teeth.

Probably not a fit

Patients with poor oral hygiene, severe parafunctional habits, or systemic conditions that contraindicate oral surgical treatment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort study aims to evaluate the esthetic, clinical, and patient-centered outcomes of immediate versus delayed dental implant placement. Participants will be divided into two groups based on the timing of their implant placement following tooth extraction. The study will assess changes in soft tissue and bone healing around the implants in both scenarios, providing insights into the best practices for dental implant procedures.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of optimal dental implant placement techniques, leading to improved esthetic and clinical outcomes for patients.

How similar studies have gone: Previous studies have shown varying success with immediate and delayed implant placements, but this specific comparison is less commonly explored, making it a valuable investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old and able to understand an informed consent
* Adequate oral hygiene to allow for implant therapy consistent with standards of care.
* Missing a single tooth in the maxillary anterior region
* Presence of adjacent natural teeth

Exclusion Criteria:

* Poor oral hygiene
* Severe parafunctional habits, for example, bruxing and clenching
* Presence of clinically active periodontal disease as expressed by probing pocket depths≥4 mm in combination with bleeding on probing.
* Conditions that might lead to a possibly lowered regenerative capacity of the bone, for example, osteoporosis and Paget's disease
* Pregnant or expecting to be pregnant
* History of drug and alcohol abuse
* History of systemic diseases that would contraindicate oral surgical treatment, for example, uncontrolled diabetes (defined as HBA1c level \>7%)
* Radiotherapy in the head and neck area,
* On certain medications like bisphosphonates or steroids currently or within the past three months
* Absence of adjacent teeth
* Unwillingness to return for the follow-up examination
* Smokers (more than 20 cigarettes per day). Subjects smoking \<20 cigarettes per day were requested to stop smoking before and after surgery

Where it's running

  • Guanghua School of Stomatology Hospital of Stomatology
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.