Comparing two types of dental implant prostheses for missing teeth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the survival rates and technical outcomes of two types of cantilever implant-supported fixed denture prosthetics: one made from monolithic zirconia bonded to a titanium base using a digital workflow, and the other made from porcelain fused to metal with a gold abutment using a conventional workflow. The study will also assess biological outcomes, wear patterns, patient-reported outcomes measures (PROMs), and time efficiency. The researchers will test the hypothesis that the type of reconstruction does not affect the survival rate and technical outcomes of the implants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Minimal age of 22 years old.
* No general medical condition which represents a contraindication to implant treatment
* Good oral hygiene (PII ≤ 20%), and healthy periodontal tissues (BOP≤ 20%)
* Two adjacent-teeth gap in posterior maxilla or mandible arch (first premolar, second premolar, first molar, second molar) with an osseointegrated regular or wide-diameter bone-level implant in a prosthetically correct position to allow occlusal screw-retention. Free-end edentulous gaps can also be included
* Presence of antagonist occlusal units

Exclusion Criteria:

* Severe bruxism or clenching habits
* Patients with inadequate oral hygiene or persistent intraoral infection
* Women who are pregnant or breast feeding at the day of inclusion
* Smokers exceeding 15 cigarettes / day, or equivalent; patients chewing tobacco
* Unable or unwilling to cooperate for the trial period
* Estimated cantilever crown mesial-distal length \> 10 mm
* Estimated implant crown height (from implant platform to occlusal contact points) \> 15 mm

Where it's running

• University of Geneva
  Geneva, Switzerland Recruiting

Study contacts

• Principal investigator: João Pitta, Dr — University of Geneva, Switzerland
• Study coordinator: João Pitta, Dr
• Email: joao.pitta@unige.ch
• Phone: +41223794088

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• UV-treated dental implants with or without melatonin in the upper back jaw

  This study tests whether UV-treated implants alone or with melatonin help regenerate bone and strengthen implants in the upper back jaw.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07853976

• Immediate molar implants with customized healing abutments in different socket classes

  This study tests placing an implant right after extracting a back tooth and using a custom healing cap to shape the gum from day one, in people needing posterior implants.

  Recruiting Plovdiv Medical University · Plovdiv · NCT07801573

• Enamel matrix derivatives to thicken gum tissue around dental implants

  We will test whether applying enamel matrix derivatives under the gum flap during implant uncovering makes gum tissue thicker and increases the width of keratinized mucosa in adults getting dental implants.

  Recruiting The University of Texas Health Science Center at San Antonio · San Antonio, Texas · NCT07053969

• Registry for Z-Systems Z5m Dental Implants

  This study is looking at how well Z-Systems Z5m dental implants made from a special ceramic material work for adults who have had or will get these implants, especially for those who prefer a metal-free option.

  Recruiting Z-Systems · Olten · NCT06007365

• Registry of Z-Systems Zirconia Dental Products for Missing Teeth

  This study is looking at how well Z-Systems zirconia dental implants work for adults with missing teeth and what their experiences are over time.

  Recruiting at 5 sites Z-Systems · Berlin and 4 other locations · NCT05427006

• Comparing immediate and delayed dental implant placement outcomes

  This study is testing whether getting dental implants right after a tooth is removed works better than waiting a while, by looking at how well the gums and bone heal in both cases.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT02814149

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.