Comparing immediate and conventional loading for dental implants
Official title: Immediate Vs. Conventional Loading for Early Implant Placement in the Esthetic Zone of Maxilla: Randomized Controlled Clinical Trial
Run by University of Belgrade · NCT06526351 · Data updated 2026-11-12
This study is testing whether getting a dental implant right away or waiting a bit longer before putting on the crown works better for people with a single failing tooth in the front of their mouth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Belgrade Academic / other |
| Locations | 1 site (Belgrade) |
| Status | Recruiting |
| Started | March 29, 2024 |
| Main results expected | March 2027 |
| Study ends | March 2027 |
| Registry record updated | July 29, 2024 |
| Trial ID | NCT06526351 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy adults over 18 with a single failing tooth in the esthetic zone of the maxilla and adequate bone volume for implant stability.
✕Probably not a fit
Patients with adjacent failing teeth, active periodontal infections, severe bruxism, or systemic conditions contraindicating surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the clinical, radiological, and patient-centered outcomes of immediate versus conventional loading protocols for dental implants placed in the esthetic zone of the maxilla. Patients with a single failing tooth will be randomly assigned to one of two treatment groups: immediate provisionalization following early implant placement or conventional loading after the same procedure. The study will involve thorough pre-operative assessments, including medical history, clinical evaluations, and imaging to ensure eligibility. The implant surgeries will be performed by experienced surgeons, with careful monitoring of implant stability during the procedure.
Why it matters
Potential benefit: If successful, this study could lead to improved outcomes and faster recovery for patients receiving dental implants.
How similar studies have gone: Previous studies have shown promising results with immediate loading protocols, suggesting potential benefits in similar approaches.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Single failing tooth in the esthetic zone of maxilla (second premolar to second premolar) * Patients older than 18 years * Healthy patients ASA I and II * Non-smokers/Light smokers (\<10 cigarettes per day) * Adequate bone volume apical and palatal to the failing tooth to allow for sufficient primary - implant stability of regular diameter implant Exclusion Criteria: * Implants adjacent to the failing teeth * Active periodontal infection * Severe bruxism * Systemic or local conditions that contraindicates dental implant surgery - Heavy smokers (\>10 cigarettes per day)
Where it's running
-
Implant Center, School of Dental Medicine, Univeristy of Blegrade
Belgrade, Serbia Recruiting
Study contacts
- Principal investigator: Aleksa Markovic, Professor — Chair of Implant Center, School of Dental Medicine
- Study coordinator: Aleksa Markovic, Professor
- Email: maleksa64@gmail.com
- Phone: +381116964380
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Dental Abutments With Different Surfaces in Two-Unit Implant Bridges
This study tests whether two different abutment surface types affect outcomes for people needing two-implant-supported, two-unit bridges in the back of the mouth.
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Lactoferrin Gel for Healing and Implant Stability in Immediate Mandibular Molars
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Melatonin Gel in Immediate Molar Implants in the Back of the jaw
In this small study, researchers test whether applying a 1% melatonin gel during immediate molar implant placement in the back of the lower jaw helps with healing and bone formation.
-
Vitamin D and dental implant osseointegration in adults with deficiency
This study tests whether giving vitamin D helps improve how well dental implants fuse with bone in adults who are deficient.
-
Buccal fat pad versus palatal pedicle flap for soft tissue coverage over zygomatic implants in a severely atrophied upper jaw
This trial will test whether using the buccal fat pad or a palatal pedicle flap gives thicker, more stable soft tissue around zygomatic implants in adults with a severely atrophied upper jaw.
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Comparing metal versus resin surgical guides for placing zygomatic implants in severely atrophic upper jaws
This trial will test whether fully metallic surgical guides or resin 3D‑printed guides give more accurate implant placement for adults who need zygomatic implants because of severe upper‑jaw bone loss.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.