Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing immediate and conventional loading for dental implants

Official title: Immediate Vs. Conventional Loading for Early Implant Placement in the Esthetic Zone of Maxilla: Randomized Controlled Clinical Trial

Run by University of Belgrade · NCT06526351 · Data updated 2026-11-12

This study is testing whether getting a dental implant right away or waiting a bit longer before putting on the crown works better for people with a single failing tooth in the front of their mouth.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of Belgrade
Academic / other
Locations1 site (Belgrade)
StatusRecruiting
StartedMarch 29, 2024
Main results expectedMarch 2027
Study endsMarch 2027
Registry record updatedJuly 29, 2024
Trial IDNCT06526351 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy adults over 18 with a single failing tooth in the esthetic zone of the maxilla and adequate bone volume for implant stability.

Probably not a fit

Patients with adjacent failing teeth, active periodontal infections, severe bruxism, or systemic conditions contraindicating surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the clinical, radiological, and patient-centered outcomes of immediate versus conventional loading protocols for dental implants placed in the esthetic zone of the maxilla. Patients with a single failing tooth will be randomly assigned to one of two treatment groups: immediate provisionalization following early implant placement or conventional loading after the same procedure. The study will involve thorough pre-operative assessments, including medical history, clinical evaluations, and imaging to ensure eligibility. The implant surgeries will be performed by experienced surgeons, with careful monitoring of implant stability during the procedure.

Why it matters

Potential benefit: If successful, this study could lead to improved outcomes and faster recovery for patients receiving dental implants.

How similar studies have gone: Previous studies have shown promising results with immediate loading protocols, suggesting potential benefits in similar approaches.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Single failing tooth in the esthetic zone of maxilla (second premolar to second premolar)
* Patients older than 18 years
* Healthy patients ASA I and II
* Non-smokers/Light smokers (\<10 cigarettes per day)
* Adequate bone volume apical and palatal to the failing tooth to allow for sufficient primary - implant stability of regular diameter implant

Exclusion Criteria:

* Implants adjacent to the failing teeth
* Active periodontal infection
* Severe bruxism
* Systemic or local conditions that contraindicates dental implant surgery - Heavy smokers (\>10 cigarettes per day)

Where it's running

  • Implant Center, School of Dental Medicine, Univeristy of Blegrade
    Belgrade, Serbia
    Recruiting

Study contacts

  • Principal investigator: Aleksa Markovic, Professor — Chair of Implant Center, School of Dental Medicine
  • Study coordinator: Aleksa Markovic, Professor
  • Email: maleksa64@gmail.com
  • Phone: +381116964380

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.