Comparing immediate and conventional loading for dental implants
Immediate Vs. Conventional Loading for Early Implant Placement in the Esthetic Zone of Maxilla: Randomized Controlled Clinical Trial
This study is testing whether getting a dental implant right away or waiting a bit longer before putting on the crown works better for people with a single failing tooth in the front of their mouth.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Belgrade Academic / other |
| Locations | 1 site (Belgrade) |
| Trial ID | NCT06526351 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the clinical, radiological, and patient-centered outcomes of immediate versus conventional loading protocols for dental implants placed in the esthetic zone of the maxilla. Patients with a single failing tooth will be randomly assigned to one of two treatment groups: immediate provisionalization following early implant placement or conventional loading after the same procedure. The study will involve thorough pre-operative assessments, including medical history, clinical evaluations, and imaging to ensure eligibility. The implant surgeries will be performed by experienced surgeons, with careful monitoring of implant stability during the procedure.
Who should consider this trial
Good fit: Ideal candidates are healthy adults over 18 with a single failing tooth in the esthetic zone of the maxilla and adequate bone volume for implant stability.
Not a fit: Patients with adjacent failing teeth, active periodontal infections, severe bruxism, or systemic conditions contraindicating surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved outcomes and faster recovery for patients receiving dental implants.
How similar studies have performed: Previous studies have shown promising results with immediate loading protocols, suggesting potential benefits in similar approaches.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Single failing tooth in the esthetic zone of maxilla (second premolar to second premolar) * Patients older than 18 years * Healthy patients ASA I and II * Non-smokers/Light smokers (\<10 cigarettes per day) * Adequate bone volume apical and palatal to the failing tooth to allow for sufficient primary - implant stability of regular diameter implant Exclusion Criteria: * Implants adjacent to the failing teeth * Active periodontal infection * Severe bruxism * Systemic or local conditions that contraindicates dental implant surgery - Heavy smokers (\>10 cigarettes per day)
Where this trial is running
Belgrade
- Implant Center, School of Dental Medicine, Univeristy of Blegrade — Belgrade, Serbia (Recruiting)
Study contacts
- Principal investigator: Aleksa Markovic, Professor — Chair of Implant Center, School of Dental Medicine
- Study coordinator: Aleksa Markovic, Professor
- Email: maleksa64@gmail.com
- Phone: +381116964380
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.