Comparing metal versus resin surgical guides for placing zygomatic implants in severely atrophic upper jaws

Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Surgical Guides in Severely Atrophic Maxilla.

Not applicable Interventional Future University in Egypt · NCT07551024

This trial will test whether fully metallic surgical guides or resin 3D‑printed guides give more accurate implant placement for adults who need zygomatic implants because of severe upper‑jaw bone loss.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment4 (estimated)
Ages18 Years and up
SexAll
SponsorFuture University in Egypt Academic / other
Locations1 site (New Cairo, Cairo Governorate)
Trial IDNCT07551024 on ClinicalTrials.gov

What this trial studies

Adults with severely atrophic maxilla who are planned for zygomatic implant‑supported fixed prostheses will be assigned to have implants placed using either a resin (3D‑printed) static surgical guide or a fully metallic static surgical guide. Surgeons will use preoperative digital planning to define implant positions, and the chosen guide will be used during the operation to direct implant placement. Postoperative imaging will be used to measure the difference between planned and actual implant positions to quantify accuracy, and patients will attend follow‑up visits to monitor healing and prosthetic outcomes. The trial focuses specifically on placement accuracy and immediate surgical performance rather than long‑term implant survival.

Who should consider this trial

Good fit: Adults aged 18 or older with a severely atrophic maxilla who are indicated for zygomatic implant‑supported fixed prostheses, have adequate mouth opening, and can consent and attend follow‑ups are ideal candidates.

Not a fit: People with uncontrolled systemic disease, active sinus or nasal infection, prior head/neck radiotherapy or bisphosphonate therapy, heavy smoking, severe parafunctional habits, pregnancy, or psychiatric conditions that affect compliance are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, a more accurate guide could reduce placement errors, lower the risk of complications, and improve fit and function of fixed prostheses for people with severe upper‑jaw bone loss.

How similar studies have performed: Standard guided‑surgery approaches have improved accuracy for many dental implants, but fully metallic static guides for zygomatic implants are relatively new and have limited published evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients ≥18 years with severely atrophic maxilla.
* Acquired maxillary defects resulting from trauma, pathology, or previous surgical resection.
* Indicated for zygomatic implant-supported fixed prosthesis.
* Sufficient mouth opening for zygomatic implants placement.
* Patients willing to sign informed consent and attend follow-ups.

Exclusion Criteria:

* Uncontrolled systemic disease affecting healing (e.g., uncontrolled diabetes, etc).
* Heavy smokers
* Previous radiotherapy or bisphosphonate therapy.
* Active sinus or nasal infection.
* Severe parafunctional habits (e.g., bruxism).
* Pregnant or lactating women.
* Patients with psychiatric disorders affecting compliance.

Where this trial is running

New Cairo, Cairo Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrophic Edentulous MaxillaZygomatic ImplantsGuided SurgeryDental ImplantAccuracy of Dental Implant PlacementZygomatic implantsSeverely atrophic maxillaSurgical guides
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.