Clinical trial Recruiting at 1 site Interventional Ages 20 to 60

Vitamin D and dental implant osseointegration in adults with deficiency

Official title: Effect of Systemic Vitamin D on Dental Implant Osseointegration in Patients With Vitamin D Deficiency: A Randomized Controlled Clinical Study)

Run by Future University in Egypt · NCT07684404 · Data updated 2026-11-12

This study tests whether giving vitamin D helps improve how well dental implants fuse with bone in adults who are deficient.

More Dental Implant trials

Quick facts

Study typeInterventional
Ages20 Years to 60 Years
SexAll
Enrollment10 (estimated)
SponsorFuture University in Egypt
Academic / other
Locations1 site (Cairo, New Cairo)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedOctober 20, 2026
Study endsNovember 1, 2026
Registry record updatedJuly 6, 2026
Trial IDNCT07684404 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–60 with vitamin D deficiency (<20 ng/mL) requiring a posterior maxillary or mandibular implant and no prior implant failure or bone-healing conditions.

Probably not a fit

Patients without vitamin D deficiency or those with conditions that impair healing despite supplementation may not experience a benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial investigates the effect of systemic vitamin D supplementation on osseointegration of dental implants in adults aged 20–60 with confirmed vitamin D deficiency. Participants receive vitamin D and are evaluated for implant integration, healing, and any complications. The study considers factors such as surgical technique, bone quality, and patient health to understand how vitamin D may influence bone mineralization and implant success. Outcomes focus on evidence of successful osseointegration and functional stability of implants. The trial is conducted at Future University in Egypt with a defined eligibility criteria to enroll suitable candidates.

Why it matters

Potential benefit: If successful, vitamin D supplementation could improve implant stability and long-term success for patients with deficiency.

How similar studies have gone: Previous work suggests nutritional status and vitamin D can impact bone healing, but direct evidence for implant osseointegration is limited and this study adds targeted data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 20-60 with diagnosed vitamin D deficiency (\<20 ng/mL).
* Edentulous area in the posterior mandible or maxilla.
* No history of previous dental implant failure, metabolic bone diseases, or conditions affecting bone healing.
* Both genders are included

Exclusion Criteria:

* Severe systemic diseases that could interfere with healing.
* Patients already on vitamin D or calcium supplements.
* Smokers or patients with poor oral hygiene practices.
* Pregnant females

Where it's running

  • Future University in Egypt (FUE)
    Cairo, New Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.