Comparing dexmedetomidine and plain ropivacaine for pain relief after heart surgery
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve Block
This study is testing if adding dexmedetomidine to a pain relief method can help patients feel better and recover faster after heart surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 20 Years to 65 Years |
| Sex | All |
| Sponsor | Fayoum University Hospital Academic / other |
| Locations | 1 site (Riyadh) |
| Trial ID | NCT05897307 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of adding dexmedetomidine to ropivacaine in ultrasound-guided pectoralis nerve blocks for patients undergoing open heart surgery. The aim is to enhance postoperative pain management and facilitate faster recovery through improved analgesia. By utilizing a less invasive technique, the study seeks to provide better patient comfort and satisfaction compared to traditional methods. The research focuses on patients who are undergoing elective cardiac surgeries, specifically those requiring midline sternotomy.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 65 years undergoing elective isolated coronary artery bypass grafting (CABG) or valve surgery with an ejection fraction greater than 35%.
Not a fit: Patients with poor left ventricular function, recent myocardial infarction, or those requiring emergency surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve postoperative pain management and recovery times for cardiac surgery patients.
How similar studies have performed: Previous studies have shown that pectoralis nerve blocks can be effective for postoperative analgesia in cardiac surgery, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 20 - 65 years, * Ejection fraction (EF) \> 35%, * Elective-isolated CABG, or Valve surgery Exclusion Criteria: * Poor left ventricular function with intra-aortic balloon pump support, * Recent myocardial infarction (last seven days), * Combined procedure (i.e., CABG + other heart/vascular procedure), * Emergency surgery, or Redo cases, * Hepatic or renal failure, creatinine \>1.5, * Patients with hemodynamic instability, preexisting infection at the site of block, allergy to local anesthetics, psychiatric illness, and patients with prolonged postoperative ventilatory course were excluded from the study.
Where this trial is running
Riyadh
- King Saud University — Riyadh, Saudi Arabia (Recruiting)
Study contacts
- Study coordinator: Mohamed Ahmed Hamed, MD
- Email: mah07@fayoum.edu.eg
- Phone: 01010509736
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.