Using acellular collagen matrix to aid wound closure after bone grafting for dental implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the use of an acellular collagen matrix to improve wound closure following a guided bone regeneration (GBR) procedure, which is necessary when there is insufficient bone volume for dental implants. Participants will undergo GBR, and if the barrier membrane remains exposed, the acellular collagen matrix will be applied to enhance healing. The study aims to evaluate the effectiveness of this approach in achieving stable wound closure and promoting bone volume increase. The methodology includes surgical site preparation, bone graft placement, and careful monitoring of healing outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Have a missing tooth or teeth which are planned to be replaced with an implant
* Need for guided bone regeneration procedure to increase the bone available for implant placement
* Systemically healthy with no contraindications for bone grafting and/or implant surgery
* No chronic sinus problems
* Non-smoker
* No need for removable temporary restorations during wound healing.

Exclusion Criteria:

* Patients that have sufficient bone volume to perform implant placement through conventional drilling protocol without any pre-implant GBR procedure
* Indications for pre-implant/pre-GBR soft tissue grafting procedure to increase existing soft tissue contours
* The need to wear a removable temporary restoration during healing

Where it's running

• The Ohio State University Graduate Periodontics Clinic
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Binnaz Leblebicioglu, DDS, MS, PhD
• Email: leblebicioglu.1@osu.edu
• Phone: 614-292-0371

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.