Comparing new bone graft materials for preserving jawbone after tooth extraction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of a new grafting material that combines demineralized freeze-dried bone allograft (DFDBA) and deproteinized bovine bone mineral (DBBM) for alveolar ridge preservation compared to a commonly used mineralized allograft. The research will assess both the dimensional changes and histological outcomes following flapless alveolar ridge preservation in patients requiring tooth extractions for future implant placement. By analyzing these factors, the study seeks to determine if the new combination material can better maintain bone volume and quality. The results will be crucial for planning successful implant-supported prostheses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients in good health
* Require the extraction of at least one premolar or molar with future implant placement
* Sufficient keratinized gingiva (equal or more than 2mm prior to extraction),
* No more than 3mm of buccal bone loss
* Flapless extraction possible
* Full mouth plaque index of less than 25%

Exclusion Criteria:

* Nicotine consumption equivalent to or more than 10 cigarettes per day
* Electronic cigarette usage
* A history of irradiation of head and neck area
* Immunodeficiency disease
* Uncontrolled systemic health problems (hypertension crisis 180/120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors)
* Previous adverse reaction to the biomaterials used
* Pregnancy/lactation, or those who are trying to become pregnant.
* Active uncontrolled or untreated periodontal disease
* Periapical lesions greater than 1 cm and soft tissue pathology

Where it's running

• Nova Southeastern University
  Fort Lauderdale, Florida, United States Recruiting

Study contacts

• Study coordinator: Andee Goldstein, DMD
• Email: ag3577@mynsu.nova.edu
• Phone: 7542599445

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Alveolar ridge preservation and whether it lowers the need for sinus floor elevation after upper back tooth extraction

  This project tries to see if filling the socket after removing upper back teeth reduces the chance you'll need a sinus lift before getting a dental implant.

  Recruiting Saint-Joseph University · Beirut, Beirut · NCT07526129

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• Demineralized versus mineralized dentin grafts to preserve the upper back tooth ridge

  We will test whether demineralized or mineralized donor dentin grafts better preserve bone after removing a single upper back tooth in healthy adults.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh · NCT07242313

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.