Combined Mediterranean Diet and Intermittent Fasting for Hypertension
Official title: The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension
Run by Fenerbahce University · NCT07189637 · Data updated 2026-11-12
This study tests whether a sodium-restricted Mediterranean diet, alone or with intermittent fasting, can lower blood pressure in adults with newly diagnosed hypertension.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 65 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Fenerbahce University Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | December 13, 2025 |
| Main results expected | December 15, 2026 |
| Study ends | January 15, 2027 |
| Registry record updated | September 25, 2026 |
| Trial ID | NCT07189637 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 40–65 with BP >140/90 mmHg, BMI 18.5–25 kg/m², newly diagnosed hypertension, and no major chronic diseases.
✕Probably not a fit
Patients with diabetes, existing cardiovascular or organ diseases, or those unable to adhere to dietary interventions may not experience benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 40–65 with newly diagnosed hypertension and normal BMI are assigned to dietary interventions that include the Mediterranean diet, intermittent fasting, or their combination, with face-to-face nutrition education. The study compares the effects on blood pressure and cardiometabolic risk markers over time. It aims to see if a sodium-limited Mediterranean approach can be as effective as the DASH-inspired plan and how intermittent fasting adds value. Eligible participants exclude those with major comorbidities or pregnancy.
Why it matters
Potential benefit: If successful, participants may experience lower blood pressure and improved cardiovascular risk profiles through a diet-based approach.
How similar studies have gone: Previous evidence supports the benefits of Mediterranean and DASH-style diets for BP reduction, with some data suggesting additive effects when combined with fasting regimens.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed hypertension patients * Individuals with blood pressure \>140/90 mmHg * Individuals with a body mass index (BMI) in the range of 18.5-25 kg/m² * Individuals aged 40-65 years Exclusion Criteria: Participants will be excluded if they have any of the following: * Type 2 Diabetes Mellitus * Type 1 Diabetes Mellitus * Cardiovascular disease * Liver disease * Kidney disease * Gastrointestinal disease * Respiratory disease * Psychiatric disorders * Women who are pregnant or breastfeeding * Severe food allergies * Current smokers or individuals consuming alcohol regularly * History of major surgery within the last 6 months
Where it's running
-
Medipol Mega University Hospital
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Mehmet KOÇAK, PhD — İstanbul Medipol Üniversitesi/Sağlık Bilim Ve Teknolojileri Araştırma Enstitüsü
- Study coordinator: Mehmet KOÇAK, PhD
- Email: mehmetkocak@medipol.edu.tr
- Phone: +90 530 097 75 33
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.