Collection of cerebrospinal fluid for cognitive disorder research
Analysis of Clinical Data and Diagnosis in Any Person Requiring an Assay of Alzheimer Biomarkers in Cerebrospinal Fluid
This study is collecting spinal fluid from people with cognitive disorders like Alzheimer's and dementia to help improve how these diseases are diagnosed.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT04844060 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on collecting cerebrospinal fluid (CSF) from patients diagnosed with various cognitive neurodegenerative diseases, including Alzheimer's disease and dementia. The aim is to create a CSF library that can help improve diagnostic accuracy and reduce errors associated with these conditions. By analyzing CSF biomarkers, researchers hope to enhance the understanding of these diseases and facilitate earlier and more accurate diagnoses. The study involves lumbar punctures for fluid collection from eligible patients with confirmed clinical diagnoses.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with a confirmed clinical diagnosis of cognitive neurodegenerative diseases who are undergoing lumbar puncture.
Not a fit: Patients who do not require a lumbar puncture or lack accurate diagnostic information may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for cognitive disorders, reducing misdiagnosis and enhancing patient care.
How similar studies have performed: Other studies utilizing CSF biomarkers have shown promise in improving diagnostic accuracy for neurodegenerative diseases, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with lumbar puncture (LP) * Patients with accurate clinical diagnosis Exclusion Criteria: * Patients who do not have a lumbar puncture * Patients for whom no accurate diagnostic information is available
Where this trial is running
Strasbourg
- Service d'évaluation et Centre Mémoire de Ressources et de Recherche (CM2R), Hôpital de jour Saint François - Pôle de Gériatrie, Hôpitaux Universitaires de Strasbourg, Hôpital de la Robertsau — Strasbourg, France (Recruiting)
Study contacts
- Principal investigator: Frédéric BLANC, MD/PhD — Hôpitaux Universitaires de Strasbourg
- Study coordinator: Frédéric BLANC, MD/PhD
- Email: frederic.blanc@unistra.fr
- Phone: 33388155858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.