Collagen and omega-3 supplements in middle-aged women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, placebo-controlled study will compare collagen peptides plus omega-3 against maltodextrin placebo in middle-aged women for 8 weeks. Participants will undergo cognitive visits, dietary tracking, and a range of physical and blood tests to assess inflammation, joint health, body composition, sleep, and quality of life. Outcomes will be analyzed using linear mixed models and t-tests to see if the supplement combination offers health benefits over placebo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Age 35 - 65 years old
* Healthy, free from known disease
* Non-smoker
* BMI of 18 - 30 kg/m2 of
* Classified as either recreationally physically active (meet the WHO guidelines for physical activity of completing at least 150-300 min moderate-intensity activity or 75-150 min of vigorous-intensity activity a week, plus muscle-strengthening activities 2 or more days a week) OR classified as sedentary (do not meet minimum activity guidelines but do occasional and/or incidental physical activity (e.g., walking to work, household activities))

Exclusion Criteria:

* Currently have a musculoskeletal injury or diagnosed condition (e.g., cardiovascular disease, osteoarthritis, diabetes, cancer, metabolic syndrome, uncontrolled hypertension, gastrointestinal disease, blood clotting disorder)
* Regularly taking prescription medication initiated in the last 3 months or unstable
* Have initiated hormone replacement therapy within the last 3 months and/or currently unstable
* BMI not between 18-30 kg/m2
* Allergy to ingredients in supplements or standardized breakfasts
* Pregnant or breastfeeding, or any other contraindications to consuming study supplements
* Lost more than 10% of body mass in past 6 months or plan on trying to lose body mass during trial period
* Currently consuming the supplements being investigated and unwilling to stop taking them
* Any known cognitive or visual impairments limiting ability to perform cognitive tests
* Unwilling to maintain current diet and physical activity levels or exercise and activity levels above recreationally active (e.g., athlete)

Where it's running

• Loughborough University
  Loughborough, United Kingdom Recruiting

Study contacts

• Study coordinator: Tom Clifford Dr Clifford
• Email: t.clifford@lboro.ac.uk
• Phone: +44 (0) 1509 228181

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Creatine or placebo to test effects on cognition, muscle strength, and body composition in middle-aged women

  This study tests whether taking creatine daily for 8 weeks improves thinking, strength, fatigue, and body composition in healthy middle-aged women compared to a placebo.

  Recruiting Loughborough University · Loughborough · NCT07729930

• L‑serine supplements with or without strength training for older adults

  This trial tries daily L‑serine supplements, alone or combined with supervised strength training, to see if they improve thinking, brain health, and physical fitness in healthy 65–85‑year‑olds.

  Recruiting University of Vienna · Vienna, State of Vienna · NCT07466290

• Wild blueberry powder for joint and gut health

  This trial will test whether taking 25 g of freeze-dried wild blueberry powder daily for 12 weeks changes gut bacteria, lowers inflammation markers, and improves joint pain in adults with multi-joint or knee arthritis.

  Recruiting University of Nevada, Las Vegas · Oklahoma City, Oklahoma · NCT06828159

• Predicting Heart Muscle Recovery After CTO Revascularization

  This study looks at whether blood tests and stress echo measurements can predict which patients with CTO will regain heart muscle function after a revascularization procedure.

  Recruiting Assiut University · Asyut, Assuit · NCT07879573

• Can the Ronnie Gardiner Method improve thinking and daily function in people with Parkinson’s

  In this 10-week program, adults with Parkinson’s disease will try the Ronnie Gardiner Method to see if it helps thinking, talking, movement, balance, and quality of life.

  Recruiting University Ghent · Ghent, Oost-Vlaanderen · NCT07863219

• Cooling During Inpatient Rehab for People with MS

  This trial tests whether wearing a cooling vest during intensive training can reduce fatigue and improve walking, strength, balance, and cognition in people with multiple sclerosis during a 3-week inpatient rehab stay.

  Recruiting Klinik Valens · Valens, Canton of St. Gallen · NCT07852156

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.