Cohort of patients with major depressive episodes focusing on sleep and biological rhythms
Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders
This study is trying to find out if certain sleep and biological markers can help identify different types of depression in patients to improve how we diagnose and treat it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT05866991 on ClinicalTrials.gov |
What this trial studies
This observational study aims to build a national cohort in France to identify biomarkers related to sleep and biological rhythms in patients suffering from major depressive episodes. By evaluating these markers, the study seeks to validate more homogeneous subgroups of patients and better understand the manifestations and pathogenesis of depressive disorders. The research is conducted through the SoPsy clinical and research network, which collaborates with the French biological psychiatry and sleep societies. The ultimate goal is to enhance the clinical practice surrounding the diagnosis and treatment of depression.
Who should consider this trial
Good fit: Ideal candidates for this study include individuals of all ages experiencing a major depressive episode as defined by DSM-5 criteria.
Not a fit: Patients who do not understand or read French or have medical conditions incompatible with the study's requirements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients with major depressive episodes.
How similar studies have performed: While there have been efforts to identify biomarkers for depression, this approach focusing on sleep and biological rhythms is relatively novel and has not been extensively tested in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with depressive episode characterized according to the DSM-5 criteria regardless of the associated characteristics and comorbidities. * Adult and child * Affiliated to a social security Exclusion Criteria: * don't understand or read french * Medical condition incompatible with administration of questionnaire * impossibility to give informed decision (subject in an emergency condition, etc.)
Where this trial is running
Paris
- Hôpital Bichat Claude Bernard — Paris, France (Recruiting)
Study contacts
- Study coordinator: Pierre Alexis GEOFFROY, PU-PH
- Email: Pierrealexis.geoffroy@aphp.fr
- Phone: 01 40 25 82 62
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.