Cognitive Behavioral Therapy for Insomnia in Veterans with Psychosis

Cognitive Behavioral Therapy For Insomnia (CBT-I) to Improve Functional Outcomes in Veterans With Psychosis

NA · VA Office of Research and Development · NCT04646200

This study is testing whether Cognitive Behavioral Therapy for Insomnia can help veterans with both psychosis and sleep problems feel better and function well in their daily lives.

Quick facts

PhaseNA
Study typeInterventional
Enrollment156 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorVA Office of Research and Development (fed)
Locations2 sites (Baltimore, Maryland and 1 other locations)
Trial IDNCT04646200 on ClinicalTrials.gov

What this trial studies

This project aims to evaluate the effectiveness of Cognitive Behavioral Therapy for Insomnia (CBT-I) in improving sleep quality and overall functioning in Veterans suffering from both psychosis and insomnia. The study will compare outcomes between participants receiving CBT-I and those in an active control group, measuring insomnia severity and health functioning at post-treatment and six months later. Additionally, the study will explore the underlying processes linking insomnia severity to functional outcomes and how psychiatric symptoms may influence the effectiveness of CBT-I.

Who should consider this trial

Good fit: Ideal candidates are Veterans aged 18 to 80 with severe mental illness and insomnia who are actively engaged in outpatient mental health services.

Not a fit: Patients currently undergoing CBT-I treatment or those planning to relocate during the study period may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance sleep quality and overall health functioning in Veterans with psychosis.

How similar studies have performed: Previous studies have shown positive outcomes for CBT-I in various populations, suggesting potential success in this specific group of Veterans.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* meet criteria for SMI: Schizophrenic disorder, affective psychosis, major depression with psychotic features, delusional disorder, brief psychotic disorder, unspecified psychotic disorder, schizotypal personality disorder
* be between the ages of 18 and 80
* be actively participating in outpatient mental health services at designated site

Exclusion Criteria:

* currently in CBT-I treatment
* planning to move out of the area during the study period

Where this trial is running

Baltimore, Maryland and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Insomnia, Psychosis, Mental Disorders, Insomnia Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.