Coenzyme Q10 and Vitamin C after gingival depigmentation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study will compare the effects of Coenzyme Q10, Vitamin C, and their combination when applied after surgical gingival depigmentation. Eligible participants are healthy adults aged 18–45 with bilateral physiologic gingival pigmentation and good oral hygiene. Treatments are given to the depigmented gingiva to see if results improve color and healing compared with standard care. The study uses a controlled design to observe clinical outcomes in a dental setting. No phase information is provided.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Systemically healthy patient of both genders aged from 18-45 years.
* Presence of bilateral physiologic gingival pigmentation in the anterior maxillary or mandibular region DOPI grades III-IV only.
* Good oral hygiene.
* Thick gingival phenotype.

Exclusion Criteria:

* Patient clinically diagnosed with periodontitis.
* Pregnant or lactating females.
* Patient with previous treatment of gingival hyperpigmentation.
* History of hypersensitivity to any study material.
* Patients who are active or previous smokers.

Where it's running

• Faculty of dental medicine for girls? ALAZHAR University, Cairo, egypt
  Nāşir, Egypt Recruiting

Study contacts

• Study coordinator: nora abdelgawad associate professor, phd
• Email: noramohamed.26@azhar.edu.eg
• Phone: +201019407891

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gingival Depigmentation with Vitamin C and Glutathione vs. Surgical Depigmentation

  This study tests whether vitamin C with glutathione injections can depigment pigmented gums as effectively as surgical depigmentation in adults.

  Recruiting Phase 2 Cairo University · Al Fayyum, Faiyum Governorate · NCT07595705

• Transabdominal vs. Transvaginal Ultrasound in high-risk pregnancies during early weeks

  This study tests whether transabdominal ultrasound can visualize fetal structures as well as transvaginal ultrasound in high-risk singleton pregnancies between 9 and 13+6 weeks.

  Recruiting Al-Azhar University · Asyut · NCT07883850

• Ultrasound-Guided PRP Injections for Nerve Regeneration in Traumatic Peripheral Nerve Injury

  This study tests whether ultrasound-guided platelet-rich plasma injections can help nerve regeneration in adults with traumatic peripheral nerve injuries.

  Recruiting Al-Azhar University · Cairo, Abbasia · NCT07879092

• Dual Trigger vs HCG Trigger for Final Maturation in Normal Responders

  In normal responders undergoing ICSI cycles, this study tests whether using a dual trigger (GnRH agonist plus hCG) improves outcomes compared with the standard hCG trigger.

  Recruiting Al-Azhar University · Cairo, Cairo Governorate · NCT07861399

• Criteria-based Rehabilitation After Tibial Fracture Fixation

  This trial tests a structured, criteria-driven rehabilitation plan against usual physiotherapy after tibial fracture surgery to see if it improves leg function.

  Recruiting Al-Azhar University · Gaza, Gaza Strip · NCT07810478

• Sexual function and quality of life in monogamous vs polygamous marriages among Egyptian men

  This is a web-based survey to see if marital structure affects erectile function and sexual quality of life in Egyptian men who are married.

  Recruiting Al-Azhar University · Cairo · NCT07783958

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.