Characterizing immune cells in malignant brain tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the immune cell profiles in patients with malignant brain tumors, focusing on both circulating leukocytes and tumor-infiltrating T cells. Participants will undergo blood sampling before surgery and continue with follow-up samples for 12 months, alongside tumor sample analysis. The goal is to correlate immune cell characteristics with oncological outcomes, providing insights into the immune response in high-grade gliomas and brain metastases.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Adult patients (≥18 years)
* Able to express informed consent
* With primary or secondary malignant brain tumor
* Requiring neurosurgical treatment (radiosurgery, stereotactic biopsy, surgery)

Exclusion Criteria:

* Patients who do not meet inclusion criteria.

Where it's running

• IRCCS San Raffaele Scientific Institute
  Milan, Milan, Italy Recruiting

Study contacts

• Study coordinator: Laura Sincinelli
• Email: sincinelli.laura@hsr.it
• Phone: 0226435568

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.