Clinical trial Recruiting at 1 site Interventional Ages 18 and up

High-intensity interval training to improve fitness in brain tumor patients

Official title: FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients: a Randomized Controlled Trial

Run by Amsterdam UMC, location VUmc · NCT06282562 · Data updated 2026-11-12

This study is testing if high-intensity interval training can help adults with stable brain tumors feel fitter compared to those who don't exercise.

More Exercise Training trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment36 (estimated)
SponsorAmsterdam UMC, location VUmc
Academic / other
Locations1 site (Amsterdam)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedAugust 15, 2026
Study endsAugust 15, 2026
Registry record updatedApril 6, 2025
Trial IDNCT06282562 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a diagnosed primary brain tumor who report reduced physical fitness and have stable disease.

Probably not a fit

Patients with a Karnofsky Performance Score below 70 or contraindications to exercise may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The FeelFit study evaluates the effectiveness of High-Intensity Interval Training (HIIT) in enhancing self-reported physical fitness among adult patients with primary brain tumors who have stable disease. Participants will be compared to a waiting-list control group to assess the impact of this exercise intervention. The study is part of the GRIP project, which focuses on improving the quality of life for brain tumor survivors. Secondary and exploratory outcomes will also be measured to provide a comprehensive understanding of the intervention's effects.

Why it matters

Potential benefit: If successful, this study could significantly enhance the physical fitness and overall quality of life for brain tumor patients.

How similar studies have gone: While there is limited data on HIIT specifically for brain tumor patients, similar exercise interventions have shown positive outcomes in improving fitness and quality of life in cancer survivors.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* reduced self-reported physical fitness;
* minimum age of 18 years;
* diagnosed with a primary brain tumor;
* stable disease, i.e. no signs of radiological or clinical tumor progression;
* no oncological treatment for at least two months prior to inclusion;
* able to speak, read and write in Dutch.

Exclusion Criteria:

* Karnofsky Performance Score \< 70;
* already participated in a HIIT program \< 1 month prior;
* contraindication of exercise.

Where it's running

  • VU University Medical Centers, location VUmc
    Amsterdam, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.