Changing the Bone-Grafting Sequence in Sinus Lifting with Implants
Official title: Effect of Changing Grafting Sequences During Sinus Lifting & Simultaneous Implant Placement in the Gained Bone Using Customized Surgical Guide: A Randomized Clinical Trial
Run by Cairo University · NCT07816107 · Data updated 2026-11-12
This trial tests whether placing bone grafting before the dental implant during sinus lifting helps bone density and implant stability in adults with at least 5 mm of vertical bone in the upper jaw.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 16 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 24, 2025 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT07816107 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with vertical bone measurements of 5 mm or slightly more who are eligible for maxillary sinus elevation, implant placement, and bone grafting.
✕Probably not a fit
Patients with significant systemic conditions, very thin bone below 5 mm, prior sinus surgery, or factors that severely impair bone metabolism may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares two surgical sequences for maxillary sinus floor augmentation with concurrent dental implants: the traditional sequence (sinus elevation, implant placement, then bone grafting) versus a modified sequence (sinus elevation, bone grafting, then implant placement). All procedures use a customized surgical guide to improve accuracy. Primary outcome is bone density, with secondary outcomes including vertical bone height gained, bone volume, and implant stability. The study aims to determine if the modified sequence yields more favorable bone and implant outcomes in patients with vertical bone height around 5 mm or more. The intervention seeks to address common complications and operative considerations to optimize implant rehabilitation in the posterior maxilla.
Why it matters
Potential benefit: If successful, patients could achieve better bone quality and implant stability with a potentially shorter or more predictable recovery.
How similar studies have gone: Previous approaches in sinus lifting and implant sequencing have shown mixed results; this study explores a novel sequence using a guided approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age more than 18 years. * Both sexes. * Patients eligible for maxillary sinus elevation, implant, and bone graft procedures. * Adequate general health for dental interventions. * Vertical bone measurement of 5 mm or slightly more. Exclusion Criteria: * Systemic conditions affecting implant success. * Patients with vertical bone measurement less than 5 mm. * Previous sinus surgery or dental implant failure. * Medication that can impair or interfere with normal bone metabolism. * History of head and neck radiotherapy. * Pregnancy.
Where it's running
-
Faculty of Dentistry, Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Ahmed Atito Said Sayed, B. D. S
- Email: ahmed.atito@dentistry.cu.edu.eg
- Phone: +201026794490
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.