Cervical prep strategies before office hysteroscopy in postmenopausal women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized study, postmenopausal women scheduled for office hysteroscopy will be assigned to one of four cervical preparation protocols: 14-day vaginal estrogen, 7-day vaginal estrogen, oral misoprostol, or no preparation. Procedures will use a vaginoscopic, no-anesthesia approach, with pain measured during the procedure and data collected on success, duration, and perioperative complications. The aim is to determine which approach improves complete visualization and minimizes discomfort. The trial is conducted at the Maternity and Neonatology Center of Tunis under the Faculty of Medicine of Tunis. Eligible participants are postmenopausal women without contraindications who provide informed consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women with postmenopausal status.
* Scheduled for office hysteroscopy for the evaluation of suspected intrauterine pathology.
* Able to understand the study procedures and provide written informed consent.

Exclusion Criteria:

* Known or suspected hormone-dependent malignancy (e.g., breast or endometrial cancer).
* Active genital tract infection.
* Contraindication or known hypersensitivity to misoprostol or vaginal estrogen.
* Refusal to undergo office hysteroscopy without anesthesia.
* Active uterine bleeding preventing adequate hysteroscopic visualization on the day of the procedure.

Where it's running

• Maternity and neonatology center of Tunis
  Tunis, Tunis Governorate, Tunisia Recruiting

Study contacts

• Study coordinator: Mohammed Amine Hannachi, Assistant professor
• Email: medaminehannachi3@gmail.com
• Phone: +21699696332

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.