AI-assisted relaxation and breathing training for postmenopausal women with chronic pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this three-arm randomized trial, postmenopausal women with non-specific chronic musculoskeletal pain are assigned to either physiotherapist-guided relaxation and breathing training, AI-assisted relaxation and breathing training, or a control group with no structured training. The AI system provides personalized guidance through a smartphone- or tablet-based program to facilitate home practice. Outcome measures focus on pain levels, sleep, mood, and quality of life, with attention to accessibility and feasibility of digital health delivery. The study leverages existing evidence that relaxation and breathwork can reduce pain and improve well-being, and evaluates whether AI-enabled guidance offers similar or added benefits in a real-world setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women aged 45 to 65 years
* Being in natural menopause (no menstrual bleeding for at least 12 months)
* Having non-specific chronic musculoskeletal pain for at least 3 months (reporting a pain intensity of at least 4 cm on the VAS)
* Using only standard analgesic medications for pain management
* Being literate
* Owning a smartphone or tablet, having the ability to listen to audio recordings, and having adequate skills to participate in online sessions
* Being willing to participate in the study and providing written informed consent

Exclusion Criteria:

* Surgical or medication-induced menopause
* Regular use of opioid analgesics, anticonvulsants, antidepressants, or similar medications
* Uncontrolled advanced cardiovascular, oncological, metabolic, rheumatologic, or neurological diseases
* Body Mass Index (BMI) of 40 kg/m² or higher
* History of major surgery or severe trauma within the past 3 months

Where it's running

• Baskent University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Aslıcan Çağlar, Asst. Prof. — Başkent University, Faculty of Health Sciences, Department of Physical Therapy and Rehabilitation
• Study coordinator: Neslihan Durutürk, Prof. Dr.
• Email: nalkan@baskent.edu.tr
• Phone: +90312 246 66 66

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.