Clinical trial Recruiting at 1 site Observational Ages 18 to 45 Women only

Menstrual cycle symptoms and female health

Official title: Prevalence of Subclinical Ovulatory Disturbances and Symptoms During the Menstrual Cycle and Their Relationship With Physical and Mental Health in Spanish Women of Reproductive Age (Prevalencia de Alteraciones Ovulatorias subclínicas y síntomas Durante el CICLO Menstrual y su relación Con la Salud física y Mental en Mujeres españolas en Edad Reproductiva).

Run by Universidad Rey Juan Carlos · NCT07699224 · Data updated 2026-11-12

This study will observe how common menstrual symptoms and related conditions appear in young adult women who have regular periods, to better understand their frequency and impact.

Quick facts

Study typeObservational
Ages18 Years to 45 Years
SexWomen only
Enrollment400 (estimated)
SponsorUniversidad Rey Juan Carlos
Academic / other
Locations1 site (Madrid)
StatusRecruiting
StartedJanuary 21, 2026
Main results expectedOctober 2026
Study endsDecember 2026
Registry record updatedJuly 13, 2026
Trial IDNCT07699224 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women aged 18–45 with natural, regular menstrual cycles who are not currently pregnant or breastfeeding and have not used hormonal contraception in the past six months.

Probably not a fit

Individuals with current pregnancy, breastfeeding, hysterectomy/oophorectomy, smoking, or recent hormonal contraception use may have limited or no direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the prevalence of menstrual cycle symptoms and related gynecologic conditions in women aged 18–45 who are naturally menstruating. By collecting data on perimenstrual and intermenstrual symptoms, the study aims to characterize how these experiences vary across individuals and life stages. The research will not involve an intervention but will document associations between hormonal fluctuations and symptoms to inform future care. Findings may highlight underdiagnosed conditions and support improved awareness of menstrual health. Participation is limited to women without recent pregnancy or hormonal contraception use who are treated at Universidad Rey Juan Carlos in Madrid, Spain.

Why it matters

Potential benefit: If successful, the study could improve understanding of how common menstrual symptoms are and help guide better diagnosis and management of related conditions.

How similar studies have gone: Prior observational work has shown high prevalence of perimenstrual symptoms and related conditions, supporting the value of this approach but specific methods may be novel in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Females
* Between 18 and 45 years
* Naturally menstruating.

Exclusion Criteria:

* Pregnant or breastfeeding.
* Hormonal contraceptive methods during the 6 months before the study.
* hysterectomy or ooforectomy.
* Smoking.

Where it's running

  • Universidad Rey Juan Carlos
    Madrid, Spain
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.