Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Can we predict which ED patients will need hospitalization and compare centers fairly?

Official title: Propensity to Hospitalize Patients From the ED in European Centers.An Observational Retrospective Quality-of-care Study

Run by Mario Negri Institute for Pharmacological Research · NCT06354764 · Data updated 2026-11-12

This observational study tests a predictive model to estimate each patient’s chance of being admitted from the emergency department, to compare hospitals fairly across centers.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment162000 (estimated)
SponsorMario Negri Institute for Pharmacological Research
Academic / other
Locations2 sites (Torino and 1 other locations)
StatusRecruiting
StartedSeptember 22, 2025
Main results expectedJanuary 2027
Study endsFebruary 2027
Registry record updatedOctober 9, 2026
Trial IDNCT06354764 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults who arrive at participating EDs between January 1, 2021 and December 31, 2023.

Probably not a fit

Patients whose hospital admission decisions are not influenced by center characteristics or whose data do not contribute to the model may see no direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study builds a predictive model using patient data from multiple European EDs to estimate the probability of hospitalization at arrival. The goal is to create a benchmark that reflects patient characteristics and ED conditions, allowing observed hospitalization rates to be compared to expected rates. No active intervention is delivered; the study observes real-world practice across participating centers. By comparing observed rates to the model’s expectations, researchers aim to evaluate center-to-center performance in a fair, adjusted way.

Why it matters

Potential benefit: If successful, centers could understand how their admission patterns compare to the benchmark and identify opportunities to optimize care pathways.

How similar studies have gone: Previous efforts with center-to-center benchmarking using risk-adjusted models have shown promise, though the exact predictive approach in this European multicenter setup is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult
* Arrived at emergency department between 1 January 2021 and 31 December 2023

Exclusion Criteria:

* None

Where it's running

  • Ospedale San Giovanni Bosco
    Torino, Italy
    Recruiting
  • Ospedale Sant'Andrea
    Vercelli, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.