Using the PIVO device to collect blood cultures in the emergency department

PIVO-ED: Protocol for Intermountain Venous Access Optimization for Blood Cultures in the Emergency Department

Observational Intermountain Health Care, Inc. · NCT07348289

This project will try using the needle-free PIVO device to collect blood cultures from emergency department patients to reduce needle sticks while keeping culture accuracy.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
SexAll
SponsorIntermountain Health Care, Inc. Academic / other
Locations1 site (Park City, Utah)
Trial IDNCT07348289 on ClinicalTrials.gov

What this trial studies

This is a prospective implementation study that will train ED staff to use the needle-free PIVO device for blood culture collection at three Intermountain Health emergency departments, with potential expansion to three additional sites. Training will occur in October 2025 and cover indications, technique, workflow integration, and Epic documentation, followed by 13 months of protocol implementation and data collection from November 2025 to October 2026. The team will monitor PIVO utilization, blood culture contamination rates, and adoption metrics to compare performance with existing collection methods. Results will determine whether the protocol should be expanded to the planned secondary sites.

Who should consider this trial

Good fit: Any emergency department patient who requires blood cultures during their ED visit at a participating site is eligible.

Not a fit: Patients who do not need blood cultures, whose blood must be drawn from indwelling central lines, or who are not treated at participating EDs are unlikely to benefit.

Why it matters

Potential benefit: If successful, patients could have fewer needle sticks and fewer contaminated blood cultures, leading to faster, more accurate diagnosis and treatment.

How similar studies have performed: Prior studies of PIVO for routine blood draws have shown comparable or lower hemolysis and contamination rates versus standard venipuncture, so this implementation builds on existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: Patients in whom blood cultures are obtained in the emergency department.

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Exclusion Criteria: none

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Where this trial is running

Park City, Utah

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SepsisDevice PerformanceEmergency Medicine
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.