Clinical trial Recruiting at 1 site Observational Ages 18 and up

AI support in emergency medicine helps doctors make differential diagnoses

Official title: Evaluation of AI Support for Differential Diagnosis in Emergency Medicine.

Run by Region Stockholm · NCT07766863 · Data updated 2026-11-12

This study tests whether a generative AI tool can help emergency doctors arrive at more accurate differential diagnoses for adult patients at Karolinska University Hospital.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorRegion Stockholm
Government
Locations1 site (Stockholm, Huddinge)
StatusRecruiting
StartedJune 8, 2026
Main results expectedJune 2029
Study endsJune 2029
Registry record updatedAugust 17, 2026
Trial IDNCT07766863 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 presenting to the ED at Karolinska University Hospital (Huddinge or Solna) with available final diagnosis data.

Probably not a fit

Patients for whom final diagnoses are unclear or not well represented in the available data may not benefit from AI assistance.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study prospectively collects emergency department cases where physicians assess patients with or without AI-supported differential diagnoses. Cases are randomized to AI-assisted or AI-free evaluation, and the resulting differential lists are compared to the final discharge diagnosis. The AI tool provides a structured list of likely diagnoses based on the initial assessment data. Analyses examine changes in diagnostic accuracy and decision-making across different clinical scenarios and information quality. The study accounts for variability in case complexity and information availability to understand AI’s impact.

Why it matters

Potential benefit: If successful, AI support could help clinicians generate more accurate differential diagnoses and improve diagnostic confidence in emergency care.

How similar studies have gone: Preliminary pilot work suggests good agreement between AI-supported diagnoses and final clinical assessments, but broader validation in routine ED practice is ongoing.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients \>18 years admitted through the emergency departments at Karolinska University Hospital in Huddinge and Solna.

Exclusion Criteria:

* Children \<18 years
* Patients without a recorded final diagnosis

Where it's running

  • Karolinska University Hospital
    Stockholm, Huddinge, Sweden
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.