CAIX-targeted 18F-T2 PET/CT imaging in solid tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional imaging study evaluates the diagnostic value of the CAIX-targeted probe 18F-T2 for PET/CT imaging in adults with solid tumors, including several gynecologic, urologic, and gastrointestinal cancers. The trial will assess how well 18F-T2 can detect tumors and will also monitor safety, tolerability, and radiation dosimetry. Participants will receive one or more PET/CT scans using the 18F-T2 tracer under controlled conditions, with standard safety monitoring. The study does not specify a control arm and focuses on feasibility and safety signals in a diverse tumor population. Enrollment is limited to adults capable of providing informed consent and meeting specified histological or suspected tumor criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All participants must meet the following criteria:

1. Written and voluntarily given Informed Consent.
2. Male or female ≥18 years of age at time of consent.
3. Have the capacity to understand the study and be willing and able to comply with all protocol requirements.
4. Participants with histologically confirmed or suspected tumors of the following types, but not limited to:

Clear Cell Renal Cell Cancer; Urothelial Carcinoma; Colorectal Cancer; Cervical Cancer; Ovarian Cancer; Head and Neck Cancer; Hepatocellular Carcinoma; Cholangiocarcinoma; Non Small Cell Lung Cancer; Small Cell Lung Cancer; Breast Cancer; Pancreatic Cancer; Endometrial Cancer; Von Hippel Lindau Disease.

Exclusion Criteria:

Participants will be excluded from participation in the study if one or more of the following criteria are met:

1. Have any serious non-malignant disease (e.g., psychiatric, infectious, autoimmune or metabolic) that may interfere with the objectives of the study or with the safety or compliance of the participant, as judged by the Investigator.
2. Have a mental impairment that may compromise the ability to give Informed Consent and comply with the requirements of the study.
3. Be a female who is pregnant or breastfeeding.

Where it's running

• Peking University First Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Meng Liu — Peking University First Hospital
• Study coordinator: Keting Tong
• Email: 1910301229@pku.edu.cn
• Phone: +86 010-83575252

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.