Breaking up sitting time for women with rheumatoid arthritis
Breaking up Sedentary Time in Rheumatoid Arthritis: Effects on Vascular Function
This study tests if taking short walking breaks during long periods of sitting can improve blood flow and artery health in women with rheumatoid arthritis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | Female |
| Sponsor | Liverpool John Moores University Academic / other |
| Locations | 1 site (Liverpool, Merseyside) |
| Trial ID | NCT05284110 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of interrupting prolonged sitting with short bouts of light walking on vascular function in women diagnosed with rheumatoid arthritis. Participants will engage in two different sessions: one involving uninterrupted sitting for four hours and another incorporating a 3-minute walk every 30 minutes. Vascular function will be measured using advanced ultrasound techniques before and after each session to assess changes in blood flow and arterial response. The study aims to provide insights into how physical activity can improve vascular health in this population.
Who should consider this trial
Good fit: Ideal candidates are adult women aged 18-60 with a diagnosis of rheumatoid arthritis who are non-smokers.
Not a fit: Patients with significant cardiovascular disease, musculoskeletal impairments, or those outside the age range may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance vascular function and overall health in women with rheumatoid arthritis.
How similar studies have performed: Other studies have shown positive outcomes with similar interventions aimed at increasing physical activity in patients with chronic conditions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult women diagnosed with RA * From the Rheumatology Clinic at the Liverpool University Hospitals NHS Foundation Trust * Aged 18-60 yr * Non-smoker for at least 6months * Able to provide written informed consent. Exclusion Criteria: * Cannot readily read and understand English. * Currently smoking or within last 6 months. * Alcohol consumption \>14units per week. * Symptoms of or established cardiovascular disease (except hypertension) * Previous stroke or myocardial infarction. * History of diabetes or respiratory disease or chronic kidney disease. * Musculoskeletal impairment/disability precluding physical activity * Unstable medication (change in medication within the 3 months) * Aged \<18 or \> 60 yr * Currently pregnant
Where this trial is running
Liverpool, Merseyside
- Research Institute for Sport and Exercise Sciences (RISES) — Liverpool, Merseyside, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Daniel Bannell, MPhil
- Email: D.J.Bannell@2015.ljmu.ac.uk
- Phone: 07786008666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.