Brain training to help with opioid addiction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to gather pilot data on neurofeedback games that utilize electroencephalogram (EEG)-based Attention Bias Modification (ABM) to help reduce drug cravings in individuals with Opioid Use Disorder (OUD). Participants will engage in games designed to train their visual attention towards non-drug-related stimuli while an EEG system monitors their brain activity. The difficulty of the games will adapt based on the participants' attention levels, as measured by the EEG. The study will involve both OUD patients and control participants matched by age and gender.

Why it matters

Who can join: the full rules

Inclusion Criteria:

OUD patient participants:

* Admitted into chemical treatment with opioid use being a reason for treatment;
* DSM-IV-TR diagnosis of OUD;
* Ability to provide informed consent;
* A minimum of a 6th grade reading level; and
* Able and willing to provide own contact information for follow-up visit(s).

Control participants:

* Age- and gender-matched to an OUD patient participant in the study;
* Ability to provide informed consent;
* A minimum of a 6th grade reading level;
* Able and willing to provide own contact information for follow-up visit(s).

Exclusion Criteria:

OUD patient participants:

* Refusal or inability to consent;
* Pregnant;
* History of serious neurological illness (e.g., Chronic seizure disorder, Wernicke-Korsakoff Syndrome, Epilepsy, Any history of seizures not caused by withdrawal from substances, Other \[please specify\]);
* Inability to see text and photos clearly on the computer display; and
* Unwillingness to change hairstyle (e.g., braids, pony tails, dreadlocks) or remove wig to accommodate application of the EEG headset, if necessary.

Control participants:

* Refusal or inability to consent;
* Pregnant;
* History of serious neurological illness (e.g., Chronic seizure disorder, Wernicke-Korsakoff Syndrome, Epilepsy, Any history of seizures, Other \[please specify\]);
* Inability to see text and photos clearly on the computer display;
* Current or previous problems using opioids, other prescription (prescribed or not prescribed) or illicit drugs;
* Regular nicotine user (e.g., cigarette smoker, e-cig user) within the past 12 months; and
* Unwillingness to change hairstyle (e.g., braids, pony tails, dreadlocks) or remove wig to accommodate application of the EEG headset, if necessary.

Where it's running

• University of Minnesota - Department of Psychiatry & Behavioral Health
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Justin Anker, PhD — University of Minnesota
• Study coordinator: Scott Burwell, PhD
• Email: burwell@umn.edu
• Phone: 612-790-9304

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• emPath platform pilot to link and keep adults with opioid use disorder in care in Durham

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• Personalized Addiction Treatment Enhancement for Opioid Use Disorder

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.