Blood Viscosity and Outcomes After Elective Brain Surgery
Official title: Association of Intraoperative Blood Viscosity With Cerebral Oxygenation and Postoperative Composite Complications in Adults Undergoing Elective Intracranial Craniotomy: A Prospective Observational Study
Run by Asan Medical Center · NCT07530393 · Data updated 2026-11-12
This study will test whether measures of blood viscosity taken during elective intracranial surgery relate to how patients recover and if they have postoperative complications.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Asan Medical Center Academic / other |
| Locations | 1 site (Seoul, Songpa) |
| Status | Recruiting |
| Started | June 23, 2026 |
| Main results expected | December 31, 2029 |
| Study ends | March 31, 2030 |
| Registry record updated | September 14, 2026 |
| Trial ID | NCT07530393 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 scheduled for elective intracranial craniotomy who require intraoperative arterial catheterization and routine arterial blood gas analysis and can provide informed consent.
✕Probably not a fit
Patients who do not experience perioperative complications or whose viscosity measures do not correlate with outcomes may see no direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational study at a single tertiary center exploring if intraoperative blood viscosity and related blood parameters are associated with cerebral oxygenation and postoperative outcomes after elective intracranial craniotomy. Adult patients undergoing elective brain surgery will have intraoperative viscosity and hematologic measures collected, along with monitoring of cerebral oxygenation, to identify potential links with complications. The goal is to improve understanding of perioperative blood flow and identify risk markers for adverse outcomes. Findings may inform perioperative management and future research in neurosurgical patients.
Why it matters
Potential benefit: If associations are found, clinicians may better predict and potentially prevent adverse postoperative events related to blood rheology.
How similar studies have gone: Previous work supports the importance of hemorheology in cerebral perfusion, but direct links to intraoperative viscosity and postoperative neurosurgical outcomes remain exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 80 years * Patients scheduled to undergo elective intracranial craniotomy * Patients requiring intraoperative arterial catheterization and routine arterial blood gas analysis * Patients who provide written informed consent Exclusion Criteria: * Emergency surgery * Patients in whom participation or follow-up is considered difficult by the investigator * Patients unable to provide informed consent
Where it's running
-
Asan Medical Center
Seoul, Songpa, South Korea Recruiting
Study contacts
- Study coordinator: Ji-Hoon Sim, MD
- Email: jihoon_sim@amc.seoul.kr
- Phone: +82-2-3010-0586
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.