Blood Flow Restriction Rehab to Improve Mobility and Balance in COPD Patients
Official title: Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients
Run by Rashid Latif Medical College · NCT07805330 · Data updated 2026-11-12
This study tests whether Blood Flow Restriction (BFR) rehabilitation can improve functional mobility and balance in people with COPD.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Rashid Latif Medical College Academic / other |
| Locations | 1 site (Lahore) |
| Status | Recruiting |
| Started | June 24, 2026 |
| Main results expected | September 24, 2026 |
| Study ends | October 25, 2026 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT07805330 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 45-60 with clinically stable COPD and FEV1 between 30% and 79% of predicted, willing to participate.
✕Probably not a fit
Patients with unstable COPD, recent major surgery, active cancer or severe hypertension may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial investigates the effects of Blood Flow Restriction (BFR) resistance exercise on functional mobility and balance in adults with COPD. Participants aged 45-60 with stable COPD are assigned to either a standard physical therapy or a BFR-assisted resistance program without tourniquets, conducted at multiple hospitals in Lahore. The study compares outcomes related to mobility and balance to determine if BFR provides additional benefit. Eligibility includes specific lung function criteria and overall clinical stability, while safety exclusions cover major surgeries, cancer, open fractures, cognitive disorders, active malignancy, and severe hypertension. The trial is led by Rashid Latif Medical College with collaboration at Arif Memorial Teaching Hospital.
Why it matters
Potential benefit: If successful, participants may experience improved mobility and balance, potentially aiding daily activities and reducing fall risk.
How similar studies have gone: Prior research in related populations has shown promise for BFR resistance training to improve strength and function, though COPD-specific results are still developing.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects who are clinically stable before study * Forced expiratory volume in 1s (FEV1)/forced vital capacity (FVC)\<70% and FEV1 ≥30% but \<80% respectively * Subjects who will be willing to take part in this study Exclusion Criteria: * Upper abdominal surgery * Lung cancer * Open fracture * Mental disorder * Active malignancy * Severe hypertension
Where it's running
-
Arif Memorial Teaching Hospital
Lahore, Pakistan Recruiting
Study contacts
- Principal investigator: Harmeen Nadeem — Arif Memorial Teaching Hospital
- Study coordinator: Aleena Waheed, Masters in Physical Therapy
- Email: alwaheed28@gmail.com
- Phone: 03214883868
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Chronic Respiratory Disease Participant Engagement
This study tests whether adults with long-term lung conditions can get comfortable with a clinical trials unit and research team before joining future trials.
-
IOS-based platform to screen, diagnose, and manage COPD and asthma
This study tests an Impulse Oscillometry system to screen for and diagnose COPD and asthma and to help predict flare-ups over about a year, involving adults in China.
-
Targeted NMES to improve breathing and leg/extra muscle strength in COPD
This study tests whether targeted neuromuscular electrical stimulation helps people with COPD see improvements in breathing muscle function and overall muscle strength.
-
AERO-007: a inhaled LABA+LAMA combination for COPD through a nebulizer
This study tests whether a nebulized LABA+LAMA combination can improve lung function in adults with COPD.
-
PBMT with a pulmonary rehab program for COPD patients
A small randomized trial tests whether adding photobiomodulation therapy before exercise in a COPD pulmonary rehab program helps improve functional capacity.
-
Controlled versus standard oxygen therapy for ICU COPD with acute exacerbation
This trial tests whether keeping oxygen levels at 88-92% helps ICU patients with an acute COPD flare more than keeping levels above 94%.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.