Clinical trial Recruiting at 1 site Interventional Ages 20 to 65

Blood Flow Restriction Rehab to Improve Mobility and Balance in COPD Patients

Official title: Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients

Run by Rashid Latif Medical College · NCT07805330 · Data updated 2026-11-12

This study tests whether Blood Flow Restriction (BFR) rehabilitation can improve functional mobility and balance in people with COPD.

More Chronic Obstructive Pulmonary Disease (COPD) trials

Quick facts

Study typeInterventional
Ages20 Years to 65 Years
SexAll
Enrollment50 (estimated)
SponsorRashid Latif Medical College
Academic / other
Locations1 site (Lahore)
StatusRecruiting
StartedJune 24, 2026
Main results expectedSeptember 24, 2026
Study endsOctober 25, 2026
Registry record updatedSeptember 4, 2026
Trial IDNCT07805330 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 45-60 with clinically stable COPD and FEV1 between 30% and 79% of predicted, willing to participate.

Probably not a fit

Patients with unstable COPD, recent major surgery, active cancer or severe hypertension may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial investigates the effects of Blood Flow Restriction (BFR) resistance exercise on functional mobility and balance in adults with COPD. Participants aged 45-60 with stable COPD are assigned to either a standard physical therapy or a BFR-assisted resistance program without tourniquets, conducted at multiple hospitals in Lahore. The study compares outcomes related to mobility and balance to determine if BFR provides additional benefit. Eligibility includes specific lung function criteria and overall clinical stability, while safety exclusions cover major surgeries, cancer, open fractures, cognitive disorders, active malignancy, and severe hypertension. The trial is led by Rashid Latif Medical College with collaboration at Arif Memorial Teaching Hospital.

Why it matters

Potential benefit: If successful, participants may experience improved mobility and balance, potentially aiding daily activities and reducing fall risk.

How similar studies have gone: Prior research in related populations has shown promise for BFR resistance training to improve strength and function, though COPD-specific results are still developing.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects who are clinically stable before study
* Forced expiratory volume in 1s (FEV1)/forced vital capacity (FVC)\<70% and FEV1 ≥30% but \<80% respectively
* Subjects who will be willing to take part in this study

Exclusion Criteria:

* Upper abdominal surgery
* Lung cancer
* Open fracture
* Mental disorder
* Active malignancy
* Severe hypertension

Where it's running

  • Arif Memorial Teaching Hospital
    Lahore, Pakistan
    Recruiting

Study contacts

  • Principal investigator: Harmeen Nadeem — Arif Memorial Teaching Hospital
  • Study coordinator: Aleena Waheed, Masters in Physical Therapy
  • Email: alwaheed28@gmail.com
  • Phone: 03214883868

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.