Barts Endocarditis Registry
Barts Endocarditis Research Registry
This registry collects health, imaging, microbiology, treatment, and outcome information from adults with infective endocarditis seen at Barts Heart Centre to learn which approaches work best.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | Queen Mary University of London Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT06434012 on ClinicalTrials.gov |
What this trial studies
This is an observational registry enrolling patients aged 16 and over with confirmed or suspected infective endocarditis, including device-related cases, who are treated or followed at Barts Heart Centre. Clinical, demographic, microbiological, imaging, surgical, and outcome data will be recorded and stored to define the local patient cohort. The registry is intended to track guideline implementation, document diagnostic and treatment patterns, and provide a baseline for future genomic and interventional trials. Data collection will support quality improvement and enable planned downstream research projects.
Who should consider this trial
Good fit: Adults (16 years and older) admitted to or attending outpatient services at Barts Heart Centre with confirmed, possible, or device-related infective endocarditis who can give informed consent are ideal candidates.
Not a fit: Patients under 16, those with pacemaker pocket infection without lead or valve involvement, or patients who refuse consent would not be included and therefore would not directly benefit from this registry.
Why it matters
Potential benefit: If successful, the registry could improve diagnosis and management of infective endocarditis at the centre and help design future trials that reduce complications and mortality.
How similar studies have performed: Hospital-based endocarditis registries have previously informed guideline uptake and trial design and improved local understanding of disease patterns, although mortality from endocarditis remains substantial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Patients aged 16 and over (Patients under 16 years of age are not admitted to Barts Heart Centre) * Patients admitted to Barts Heart Centre with confirmed Endocarditis (see above) * Patients attending outpatients with confirmed/suspected Endocarditis * Patients with possible IE who complete treatment for endocarditis * Patients with cardiac device related Endocarditis * Patients with the ability to provide informed consent Exclusion Criteria: * • Patients with pacemaker pocket infection with no evidence of pacemaker lead or valve infection * Patients who refuse consent to be included in the research database * Patients with "rejected" endocarditis
Where this trial is running
London
- St Bartholomews Hospital — London, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Simon Woldman, MSc — St Bartholomews Hospital
- Study coordinator: Innocent Bvekerwa, MSc
- Email: i.bvekerwa@nhs.net
- Phone: 07852209005
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.