Assessing risk factors and prognosis for aortic valve diseases
Aortic Valve Diseases RISk facTOr assessmenT and Prognosis modeL Construction (ARISTOTLE)
Sun Yat-sen University · NCT06069232
This study is trying to find out what factors affect the health of people with aortic valve disease while they're in the hospital, to help doctors make better decisions about their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Sun Yat-sen University (other) |
| Locations | 7 sites (Guangzhou, Guangdong and 6 other locations) |
| Trial ID | NCT06069232 on ClinicalTrials.gov |
What this trial studies
This multicenter cohort study focuses on patients diagnosed with aortic valve disease, including aortic insufficiency and aortic stenosis, during hospitalization. The study aims to evaluate prognostic risk factors and construct a predictive model to guide clinical decision-making. By following patients over time, the study will assess all-cause mortality and cardiovascular events as primary and secondary outcomes, respectively.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with aortic valve disease.
Not a fit: Patients who have undergone aortic valve replacement at baseline will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the risk factors associated with aortic valve diseases, leading to improved patient management and outcomes.
How similar studies have performed: Other studies have successfully identified risk factors and prognostic models for cardiovascular diseases, suggesting that this approach has potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥ 18 * diagnosed as aortic valve disease Exclusion Criteria: * aortic valve replacement at baseline
Where this trial is running
Guangzhou, Guangdong and 6 other locations
- First Affiliated Hospital, Sun Yat-Sen University — Guangzhou, Guangdong, China (RECRUITING)
- Third Affiliated Hospital, Sun Yat-Sun University — Guangzhou, Guangdong, China (RECRUITING)
- Jieyang People's Hospital — Jieyang, Guangdong, China (RECRUITING)
- Second Affiliated Hospital of Shantou University Medical College — Shantou, Guangdong, China (RECRUITING)
- Eighth Affiliated Hospital, Sun Yat-Sen University — Shenzhen, Guangdong, China (RECRUITING)
- Affiliated Hospital of Guangdong Medical University — Zhanjiang, Guangdong, China (RECRUITING)
- Zhongshan People's Hospital — Zhongshan, Guangdong, China (RECRUITING)
Study contacts
- Principal investigator: xiaodong zhuang, PhD — First Affiliated Hospital, Sun Yat-Sen University
- Study coordinator: xiaodong zhuang, PhD
- Email: zhuangxd3@mail.sysu.edu.cn
- Phone: +86 13760755035
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aortic Valve Disease, aortic stenosis, aortic valve insufficiency, risk factor, prediction model