Assessing lung tumor motion with dynamic MRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to improve the treatment of lung tumors by using dynamic MRI to assess tumor motion during the respiratory cycle. It compares the effectiveness of dynamic MRI against the standard 4D CT imaging in tailoring the safety margins for stereotactic body radiotherapy (SBRT). Patients receiving SBRT for lung tumors located below the carina will participate, undergoing both imaging techniques to evaluate tumor motion and its impact on treatment outcomes. The study also includes monitoring patient anxiety levels during imaging sessions to understand its influence on breathing patterns.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Accepted for SBRT treatment of one or more caudally situated lung targets (NSCLC or metastases), i.e. below the carina.
* Age ≥ 18 years
* Adequate clinical condition to maintain immobilised position for at least 30 minutes
* Adequate Swedish skills and cognitive function to understand study information and to fill in the questionnaire

Exclusion Criteria:

* Pregnancy or breastfeeding, or planned pregnancy or breastfeeding, during treatment
* Contraindication for MRI examination
* Otherwise incapable of participating in study

Where it's running

• Karolinska University Hospital
  Stockholm, Sweden Recruiting

Study contacts

• Principal investigator: Eva Onjukka, PhD — Karolinska University Hospital/Karolinska Institutet
• Study coordinator: Mattias Hedman, MD PhD
• Email: mattias.hedman@regionstockholm.se
• Phone: +46812370000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.