Clinical trial Recruiting at 1 site Observational Ages 18 and up

Assessing exercise capacity in patients undergoing heart surgery

Official title: Cardiopulmonary Exercise Testing in the Prediction of Post-operative Complications in Patients Undergoing Coronary Artery Bypass Graft Surgery

Run by St. Anne's University Hospital Brno, Czech Republic · NCT06702059 · Data updated 2026-11-12

This study is testing if certain exercise measurements can help predict complications and survival in older patients with health issues who are having heart surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment130 (estimated)
SponsorSt. Anne's University Hospital Brno, Czech Republic
Academic / other
Locations2 sites (Brno, Czech Republic and 1 other locations)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedDecember 31, 2027
Study endsApril 1, 2028
Registry record updatedMay 15, 2025
Trial IDNCT06702059 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients scheduled for coronary artery bypass graft surgery.

Probably not a fit

Patients who are unable to perform cardiopulmonary exercise testing or those undergoing off-pump revascularization may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the prognostic role of cardiopulmonary exercise testing (CPET) in patients scheduled for coronary artery bypass graft surgery. It aims to determine whether specific parameters from CPET, such as the partial pressure of end-tidal carbon dioxide and the VE/VCO2 slope, can predict postoperative complications and mortality. The study focuses on high-risk patients, particularly the elderly with significant comorbidities and frailty, to improve pre-operative risk assessment. By analyzing these parameters, the study seeks to enhance the understanding of postoperative outcomes in cardiothoracic surgery.

Why it matters

Potential benefit: If successful, this study could lead to improved risk stratification and better management of patients undergoing heart surgery, potentially reducing postoperative complications.

How similar studies have gone: While limited studies have explored CPET in cardiothoracic surgery, recent findings suggest its feasibility and potential prognostic value, indicating a promising area of investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients scheduled for coronary artery bypass graft surgery

Exclusion Criteria:

* not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery

Where it's running

  • Centre of Cardiovascular and Transplantation Surgery
    Brno, Czech Republic, Czechia
    Recruiting
  • St. Anne's University Hospital in Brno
    Brno, Czech Republic, Czechia
    Active not recruiting

Study contacts

  • Principal investigator: Ivan Cundrle, prof., M.D. — St. Anne's University Hospital
  • Study coordinator: Ivan Cundrle, prof., M.D.
  • Email: Ivan.Cundrle@fnusa.cz
  • Phone: 00420 543182553

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.