Assessing exercise capacity in patients undergoing heart surgery
Cardiopulmonary Exercise Testing in the Prediction of Post-operative Complications in Patients Undergoing Coronary Artery Bypass Graft Surgery
This study is testing if certain exercise measurements can help predict complications and survival in older patients with health issues who are having heart surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 130 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | St. Anne's University Hospital Brno, Czech Republic Academic / other |
| Locations | 2 sites (Brno, Czech Republic and 1 other locations) |
| Trial ID | NCT06702059 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the prognostic role of cardiopulmonary exercise testing (CPET) in patients scheduled for coronary artery bypass graft surgery. It aims to determine whether specific parameters from CPET, such as the partial pressure of end-tidal carbon dioxide and the VE/VCO2 slope, can predict postoperative complications and mortality. The study focuses on high-risk patients, particularly the elderly with significant comorbidities and frailty, to improve pre-operative risk assessment. By analyzing these parameters, the study seeks to enhance the understanding of postoperative outcomes in cardiothoracic surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled for coronary artery bypass graft surgery.
Not a fit: Patients who are unable to perform cardiopulmonary exercise testing or those undergoing off-pump revascularization may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved risk stratification and better management of patients undergoing heart surgery, potentially reducing postoperative complications.
How similar studies have performed: While limited studies have explored CPET in cardiothoracic surgery, recent findings suggest its feasibility and potential prognostic value, indicating a promising area of investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled for coronary artery bypass graft surgery Exclusion Criteria: * not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery
Where this trial is running
Brno, Czech Republic and 1 other locations
- Centre of Cardiovascular and Transplantation Surgery — Brno, Czech Republic, Czechia (Recruiting)
- St. Anne's University Hospital in Brno — Brno, Czech Republic, Czechia (Active_not_recruiting)
Study contacts
- Principal investigator: Ivan Cundrle, prof., M.D. — St. Anne's University Hospital
- Study coordinator: Ivan Cundrle, prof., M.D.
- Email: Ivan.Cundrle@fnusa.cz
- Phone: 00420 543182553
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.