Assessing exercise capacity in patients undergoing heart surgery
Official title: Cardiopulmonary Exercise Testing in the Prediction of Post-operative Complications in Patients Undergoing Coronary Artery Bypass Graft Surgery
Run by St. Anne's University Hospital Brno, Czech Republic · NCT06702059 · Data updated 2026-11-12
This study is testing if certain exercise measurements can help predict complications and survival in older patients with health issues who are having heart surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 130 (estimated) |
| Sponsor | St. Anne's University Hospital Brno, Czech Republic Academic / other |
| Locations | 2 sites (Brno, Czech Republic and 1 other locations) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | December 31, 2027 |
| Study ends | April 1, 2028 |
| Registry record updated | May 15, 2025 |
| Trial ID | NCT06702059 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients scheduled for coronary artery bypass graft surgery.
✕Probably not a fit
Patients who are unable to perform cardiopulmonary exercise testing or those undergoing off-pump revascularization may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the prognostic role of cardiopulmonary exercise testing (CPET) in patients scheduled for coronary artery bypass graft surgery. It aims to determine whether specific parameters from CPET, such as the partial pressure of end-tidal carbon dioxide and the VE/VCO2 slope, can predict postoperative complications and mortality. The study focuses on high-risk patients, particularly the elderly with significant comorbidities and frailty, to improve pre-operative risk assessment. By analyzing these parameters, the study seeks to enhance the understanding of postoperative outcomes in cardiothoracic surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved risk stratification and better management of patients undergoing heart surgery, potentially reducing postoperative complications.
How similar studies have gone: While limited studies have explored CPET in cardiothoracic surgery, recent findings suggest its feasibility and potential prognostic value, indicating a promising area of investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled for coronary artery bypass graft surgery Exclusion Criteria: * not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery
Where it's running
-
Centre of Cardiovascular and Transplantation Surgery
Brno, Czech Republic, Czechia Recruiting -
St. Anne's University Hospital in Brno
Brno, Czech Republic, Czechia Active not recruiting
Study contacts
- Principal investigator: Ivan Cundrle, prof., M.D. — St. Anne's University Hospital
- Study coordinator: Ivan Cundrle, prof., M.D.
- Email: Ivan.Cundrle@fnusa.cz
- Phone: 00420 543182553
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.