Clinical trial Recruiting at 5 sites Observational Ages 18 and up

Assessing early brain damage in cardiac arrest patients upon ICU admission

Official title: Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest

Run by AfterROSC · NCT05606809 · Data updated 2026-11-12

This study is testing ways to measure early brain damage in adults who are in a coma after cardiac arrest to help doctors make better decisions about their care.

More Cardiac Arrest trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment4500 (estimated)
SponsorAfterROSC
Academic / other
Locations5 sites (Nantes, Pays de Loire and 4 other locations)
StatusRecruiting
StartedNovember 2, 2022
Main results expectedSeptember 30, 2027
Study endsDecember 31, 2027
Registry record updatedNovember 4, 2026
Trial IDNCT05606809 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients who are comatose after experiencing cardiac arrest and are admitted to the intensive care unit.

Probably not a fit

Patients who experience intra-hospital cardiac arrest or are minors will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate early brain damage assessment scores in adult patients admitted to the intensive care unit after experiencing cardiac arrest. It focuses on patients who are comatose upon admission, utilizing various prediction models to stratify the risk of unfavorable outcomes and identify candidates for post-resuscitation interventions. The study seeks to improve decision-making processes for resource allocation and management of patients' proxies in critical care settings.

Why it matters

Potential benefit: If successful, this study could enhance the ability to predict outcomes for cardiac arrest patients, leading to better-targeted interventions and improved survival rates.

How similar studies have gone: Other studies have shown success in using early assessment scores to predict outcomes in post-cardiac arrest patients, indicating that this approach is supported by existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all adult patients, major, admitted to intensive care after cardiac arrest (after both in and out-of hospital cardiac arrest),
* comatose (defined by Glasgow score ≤ 8) on admission,

Exclusion Criteria:

* cardiac arrest occurring intra-hospital,
* minor patient,
* major patient under guardianship,
* protected persons,
* prior inclusion in the study

Where it's running

  • CHU Nantes
    Nantes, Pays de Loire, France
    Recruiting
  • Hopital Jacques Cartier
    Massy, France
    Recruiting
  • Clinique Ambroise Paré
    Neuilly-sur-Seine, France
    Recruiting
  • APHP, Cochin
    Paris, France
    Recruiting
  • CH Versailles
    Versailles, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.