Assessing early brain damage in cardiac arrest patients upon ICU admission
Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest
This study is testing ways to measure early brain damage in adults who are in a coma after cardiac arrest to help doctors make better decisions about their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | AfterROSC Academic / other |
| Locations | 5 sites (Nantes, Pays de Loire and 4 other locations) |
| Trial ID | NCT05606809 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate early brain damage assessment scores in adult patients admitted to the intensive care unit after experiencing cardiac arrest. It focuses on patients who are comatose upon admission, utilizing various prediction models to stratify the risk of unfavorable outcomes and identify candidates for post-resuscitation interventions. The study seeks to improve decision-making processes for resource allocation and management of patients' proxies in critical care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients who are comatose after experiencing cardiac arrest and are admitted to the intensive care unit.
Not a fit: Patients who experience intra-hospital cardiac arrest or are minors will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the ability to predict outcomes for cardiac arrest patients, leading to better-targeted interventions and improved survival rates.
How similar studies have performed: Other studies have shown success in using early assessment scores to predict outcomes in post-cardiac arrest patients, indicating that this approach is supported by existing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all adult patients, major, admitted to intensive care after cardiac arrest (after both in and out-of hospital cardiac arrest), * comatose (defined by Glasgow score ≤ 8) on admission, Exclusion Criteria: * cardiac arrest occurring intra-hospital, * minor patient, * major patient under guardianship, * protected persons, * prior inclusion in the study
Where this trial is running
Nantes, Pays de Loire and 4 other locations
- CHU Nantes — Nantes, Pays de Loire, France (Recruiting)
- Hopital Jacques Cartier — Massy, France (Recruiting)
- Clinique Ambroise Paré — Neuilly-sur-Seine, France (Recruiting)
- APHP, Cochin — Paris, France (Recruiting)
- CH Versailles — Versailles, France (Recruiting)
Study contacts
- Study coordinator: Jean Baptiste Lascarrou, MD, PhD
- Email: jeanbaptiste.lascarrou@chu-nantes.fr
- Phone: +33240087376
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.