Assessing cognitive function in patients with focal brain injuries

Cognitive Function Assessment in Patients With Focal Brain Injury

Observational University Hospital, Grenoble · NCT04182087

This study looks at how specific brain injuries affect thinking and memory in patients to better understand their recovery.

Quick facts

Study typeObservational
Enrollment400 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUniversity Hospital, Grenoble Academic / other
Locations1 site (Grenoble)
Trial IDNCT04182087 on ClinicalTrials.gov

What this trial studies

This observational study focuses on understanding cognitive deficits associated with focal brain injuries by building a comprehensive database of behavioral responses during cognitive tasks. It targets patients with specific types of brain lesions, such as those resulting from strokes or surgical resections, to analyze how these lesions affect various cognitive functions. The study aims to collect extensive data to clarify the relationship between lesion characteristics and cognitive performance, ultimately enhancing our understanding of brain function and recovery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-70 with a single focal brain lesion documented by MRI.

Not a fit: Patients with multiple lesions, significant somatic disorders affecting cognition, or those who are pregnant or nursing may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients with cognitive impairments due to focal brain injuries.

How similar studies have performed: Previous studies have successfully utilized similar approaches to investigate cognitive functions in patients with focal brain injuries, contributing valuable insights to the field.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male and female patients, 18-70 years old
* A single, focal anatomical lesion of a given cerebral territory (post vascular, post surgical resection) documented by MRI
* Intellectual ability and understanding of instructions compatible with the cognitive tasks to be performed

Exclusion Criteria:

* Patient deprived of liberty
* Somatic disorder likely to affect cognitive abilities
* Pregnant or nursing woman

Where this trial is running

Grenoble

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Focal Brain InjuryCognitionBehavioral performanceCortical resectionStroke
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.