Analyzing serum indicators in elderly patients after gastrointestinal surgery
Official title: Correlation Analysis of Postoperative Delirium and Postoperative Neurocognitive Disorder in Elderly Patients With Gastrointestinal Neoplasms
Run by Xuanwu Hospital, Beijing · NCT06466096 · Data updated 2026-11-12
This study is testing how certain blood markers in older patients who have gastrointestinal surgery relate to whether they experience confusion after surgery and any long-term thinking problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years to 100 Years |
| Sex | All |
| Enrollment | 165 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | October 18, 2024 |
| Main results expected | July 1, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | April 3, 2025 |
| Trial ID | NCT06466096 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are elderly patients aged 65 and above who are undergoing surgical procedures for gastrointestinal neoplasms.
✕Probably not a fit
Patients with a history of psychiatric or neurological disorders, or those unable to complete cognitive assessments, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the differences in serum indicators among elderly patients with gastrointestinal neoplasms who experience postoperative delirium (POD) and those who do not develop long-term postoperative neurocognitive disorders (pNCD). Patients aged 65 and older undergoing surgery at Xuanwu Hospital will have their serum indicators measured before and after surgery, alongside cognitive assessments using the Montreal Cognitive Assessment (MoCA). The study will classify patients into POD and non-POD groups and further assess neurocognitive function in the POD group to identify the presence of pNCD. The findings may provide insights into the relationship between serum indicators and cognitive outcomes in this population.
Why it matters
Potential benefit: If successful, this study could help identify serum indicators that predict cognitive outcomes in elderly patients after gastrointestinal surgery.
How similar studies have gone: While similar studies have explored cognitive outcomes in surgical patients, this specific correlation analysis of serum indicators in elderly patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥65 years of age who have undergone surgical anesthesia of gastrointestinal neoplasms; Sign informed consent. Exclusion Criteria: * Inability to complete cognitive function assessment; Illiteracy, hearing impairment or visual impairment; He has a history of epilepsy, depression, schizophrenia, Alzheimer's disease and other psychiatric and neurological diseases.
Where it's running
-
Xuanwu Hospital, Capital Medical University
Beijing, China Recruiting
Study contacts
- Study coordinator: Lei Zhao, Doctor's
- Email: zhaoalei@sina.com
- Phone: +8613811035886
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.