Analyzing serum indexes in elderly spinal surgery patients with postoperative delirium
Correlation Analysis of Postoperative Delirium and Postoperative Neurocognitive Disorder in Elderly Spinal Surgery Patients
Xuanwu Hospital, Beijing · NCT06466083
This study is trying to see if there are differences in blood test results between older patients who experience confusion after spinal surgery and those who don’t, to better understand their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 165 (estimated) |
| Ages | 65 Years to 100 Years |
| Sex | All |
| Sponsor | Xuanwu Hospital, Beijing (other) |
| Locations | 1 site (Beijing) |
| Trial ID | NCT06466083 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the differences in serum indexes between elderly patients who experience postoperative delirium (POD) after spinal surgery and those who do not develop long-term postoperative neurocognitive disorders (pNCD). Participants aged 65 and older will undergo cognitive assessments before surgery and delirium evaluations within a week post-surgery. The study will compare serum index levels before and after surgery to explore correlations between POD and pNCD. The research is conducted at Xuanwu Hospital under routine anesthetic management.
Who should consider this trial
Good fit: Ideal candidates are elderly patients aged 65 and older who are scheduled for spinal surgery.
Not a fit: Patients with a history of significant psychiatric or neurological disorders, or those unable to complete cognitive assessments, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of postoperative complications in elderly patients, potentially leading to improved management strategies.
How similar studies have performed: While there have been studies on postoperative delirium and neurocognitive disorders, this specific correlation analysis in elderly spinal surgery patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥65 years of age who have undergone spinal surgery anesthesia; Sign informed consent Exclusion Criteria: * Inability to complete cognitive function assessment; Illiteracy, hearing impairment or visual impairment; He has a history of epilepsy, depression, schizophrenia, Alzheimer's disease and other psychiatric and neurological diseases
Where this trial is running
Beijing
- Xuanwu Hospital, Capital Medical University, Beijing, 100053 — Beijing, China (RECRUITING)
Study contacts
- Study coordinator: lei zhao
- Email: zhaoalei@sina.com
- Phone: +8613811035886
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Delirium, Postoperative Neurocognitive Disorder, Spinal Surgery, postoperative delirium, postoperative neurocognitive disorder, serum indexes, spinal surgery