Analyzing genetic mutations in papillary thyroid tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize the mutational profile of papillary thyroid carcinomas (PTC) by analyzing tumor samples using a specialized Mass ARRAY platform. The study focuses on identifying common somatic mutations in the MAP kinase pathway, which are present in a significant percentage of PTC cases. By correlating the molecular profiles with clinical and prognostic characteristics, the research seeks to enhance understanding of the disease and inform targeted therapies. The approach is sensitive, rapid, and cost-effective, allowing for comprehensive genetic analysis in a single experiment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with papillary thyroid cancer
* patients whose tumor tissue can be recovered for genetic analysis

Exclusion Criteria:

* patients who did not give consent
* patients lost to follow-up
* tumor samples not suitable for genetic analysis

Where it's running

• Istituto Auxologico Italiano
  Milan, Mi, Italy Recruiting

Study contacts

• Principal investigator: Laura Fugazzola, MD PhD — Istituto Auxologico Italiano-Milan, Italy
• Study coordinator: Marina Muzza, PhD
• Email: m.muzza@auxologico.it
• Phone: +390261191

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing biopsy results to surgical samples in thyroid cancer

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.