Evaluating thermal ablation and surgery for low-risk papillary thyroid cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the clinical outcomes of ultrasound-guided thermal ablation compared to traditional thyroid surgery for patients with low-risk papillary thyroid carcinoma. It will also focus on developing and validating an artificial intelligence model to predict the outcomes of thermal ablation in this patient population. The study will include patients aged 18 to 80 with confirmed papillary thyroid carcinoma and specific tumor characteristics, and will follow them for at least 12 months post-treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. patients age between 18 and 80 year old, both sex
2. papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
3. the largest diameter ≤2.0 cm
4. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, nech and chest CT
5. follow-up period ≥12 months,

Exclusion Criteria:

1. patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
2. history of neck radiation
3. history of thyroid surgery
4. coagulation disorder
5. serious heart, respiratory, liver, or renal failure
6. dysfunction of the vocal cord on the opposite side

Where it's running

• Chinese PLA General Hospital
  Beijing, China Recruiting

Study contacts

• Study coordinator: Lin Yan, MD
• Email: gemma-y@163.com
• Phone: 13811237313

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Analyzing genetic mutations in papillary thyroid tumors

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.