Ultrasound-guided thermal ablation for treating papillary thyroid cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the long-term outcomes of ultrasound-guided thermal ablation as a treatment for papillary thyroid carcinoma. It is a multicenter observational study that aims to predict clinical outcomes for patients undergoing this procedure. The study focuses on patients with small tumors and no evidence of aggressive cancer characteristics. Data will be collected over a follow-up period of at least 12 months to assess effectiveness and safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. patients age between 18 and 80 year old, both sex
2. papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
3. the largest diameter ≤2.0 cm
4. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT
5. follow-up period ≥12 months

Exclusion Criteria:

1. patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
2. history of neck radiation
3. coagulation disorder, serious heart, respiratory, liver, or renal failure
4. dysfunction of the vocal cord on the opposite side

Where it's running

• Chinese PLA General Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Yukun Luo — Chinese PLA General Hospital
• Study coordinator: Lin Yan, MD
• Email: gemma-y@163.com
• Phone: 13811237313 ext 86

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Online follow-up for patients with papillary thyroid cancer

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• Evaluating thermal ablation and surgery for low-risk papillary thyroid cancer

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• Comparing biopsy results to surgical samples in thyroid cancer

  This study is testing if the results from small needle biopsies of thyroid cancer match up with those from larger surgical samples to help doctors make better treatment decisions for patients with papillary thyroid cancer.

  Recruiting University of Calgary · Calgary, Alberta · NCT06133374

• Analyzing genetic mutations in papillary thyroid tumors

  This study is trying to see if analyzing genetic changes in thyroid tumors can help doctors understand the disease better and find better treatments for patients with papillary thyroid cancer.

  Recruiting Istituto Auxologico Italiano · Milan, MI · NCT05766098

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.