Clinical trial Recruiting at 1 site Interventional Ages 18 and up

AI-powered personalized lifestyle plan to lower blood pressure

Official title: Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial

Run by National Bureau of Economic Research, Inc. · NCT07725250 · Data updated 2026-11-12

A digital health program uses AI to tailor lifestyle tips to people with hypertension and tries to help them lower their blood pressure.

More Hypertension trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment3000 (estimated)
SponsorNational Bureau of Economic Research, Inc.
Academic / other
Locations1 site (La Jolla, California)
StatusRecruiting
StartedApril 10, 2026
Main results expectedApril 30, 2027
Study endsApril 30, 2027
Registry record updatedJuly 24, 2026
Trial IDNCT07725250 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with Stage I–II hypertension (BP 140/90 or higher) who can make informed decisions and can participate without mobility aids.

Probably not a fit

Patients with pregnancy or under 18, those in care settings with high vulnerability, or those needing supplemental oxygen may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial tests a digital health tool that collects daily habit data and blood pressure readings to generate personalized lifestyle recommendations. The AI/ML system delivers tailored guidance in low- or high-intensity formats, integrated into regular care at UC San Diego Health. Outcomes will compare blood pressure changes across diverse patient groups to refine usability and effectiveness of the program.

Why it matters

Potential benefit: If successful, participants may see greater reductions in blood pressure through personalized, easy-to-use lifestyle changes.

How similar studies have gone: Prior studies using digital health and AI-driven personalization have shown promise in improving cardiovascular risk factors, though experiences vary by population and implementation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Stage I-II hypertension (average clinical readings of blood pressure over 140/90)
* Adequate decisional capacity to make a choice about participating in this research study
* Fully ambulatory (not requiring assistive device such as a cane, wheelchair, walker, etc.)

Exclusion Criteria:

* Pregnancy
* Under age 18 years
* Institutionalized individuals who are likely to be vulnerable
* Dependent on supplemental oxygen

Where it's running

  • University of California, San Diego
    La Jolla, California, United States
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.