Agreement of Two OCT Biometers: A Pilot Study

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot study compares measurements from two OCT biometers, UNITY Dx and Anterion, in a single-visit assessment. It includes adults with normal corneas, keratoconus, prior corneal laser treatment, habitual contact lens wear, or dry eye, and collects data from one eye per participant. Subjects are grouped by condition and undergo imaging with both devices to evaluate agreement and repeatability. The study is sponsored by Alcon Research and conducted at The Eye Institute of Utah in Salt Lake City. Outcomes focus on measurement concordance between devices rather than clinical endpoints.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Have healthy, clear corneas for the normal cohort;
* Have documented keratoconus for the keratoconus cohort;
* Have reported use of daily contact lens use for the contact lens cohort;
* Have documented dry eye, consisting of signs and symptoms for the dry eye cohort;
* Has had previous keratorefractive surgery for the post-refractive surgery cohort;
* Able to comprehend and sign the informed consent form.

Exclusion Criteria:

* Active ocular infection or inflammation;
* Unable to fixate due to nystagmus or other eye movement abnormality (e.g., significant strabismus);
* Any ocular disease and/or condition that, in the investigator's clinical judgment, may put the subject at significant risk, may compromise study result or may interfere significantly with the subject's participation in the study.

Where it's running

• The Eye Institute of Utah
  Salt Lake City, Utah, United States Recruiting

Study contacts

• Study coordinator: Alcon Call Center
• Email: alcon.medinfo@alcon.com
• Phone: 1-888-451-3937

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.