Endoscopic injection of Exparel for craniofacial pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of endoscopically guided injection of Exparel (Bupivacaine) for treating craniofacial pain, including conditions like migraines and cluster headaches. The study employs a prospective, randomized, double-blinded, placebo-controlled, and cross-over design to assess the impact of Exparel on pain relief and functional outcomes. Participants will receive either the active treatment or a saline placebo, with the aim of determining if Exparel can provide significant pain relief compared to standard topical Lidocaine. The trial is designed to gather robust data on the efficacy of this novel approach to pain management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a chief complaint of craniofacial pain (migraine, cluster headache, trigeminal autonomic cephalgia, sphenopalatine ganglioneuraligia, paroxysmal hemicrania) who has Stanford Pain \& ENT clinic visit

Exclusion Criteria:

* age \<18 or \>80
* pregnant women
* economically disadvantaged (not able to afford clinic visits/treatments)
* decisionally impaired (unable to obtain informed consent)
* has allergy to bupivacaine
* unable or unwilling to participate plans to participate in another clinical study at any time during this study

Where it's running

• Peter H Hwang
  Stanford, California, United States Recruiting

Study contacts

• Principal investigator: Peter Hwang, MD — Stanford University
• Study coordinator: Peter Hwang, MD
• Email: hwangph@stanford.edu
• Phone: (650) 723-5281

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.