Sponsor or institution

Clinical trials and research at St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC

• 7NIH research projects

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how certain bacterial elements insert DNA in a specific direction.

  This study is exploring a special tool called CRISPR-associated transposons that can help scientists insert DNA into specific spots in genes, and it aims to understand how this tool works in one direction, which could lead to better ways to fix genetic disorders.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-11180723

• Understanding genetic causes of childhood epilepsy

  This study is looking at the genetic reasons behind serious brain disorders in children that cause seizures and are hard to treat, with the hope of finding better, personalized treatments for those who haven't been diagnosed yet.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-11071728

• Understanding how certain cells turn into rhabdomyosarcoma, a type of cancer.

  This study is looking into how certain cells that aren't muscle cells can turn into rhabdomyosarcoma, a type of aggressive cancer that affects kids, to help us understand why this happens and find better ways to treat it.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-11071727

• Investigating the role of SOX8 in muscle development and a type of childhood cancer.

  This study is looking at how a gene called SOX8 affects muscle growth and its connection to rhabdomyosarcoma, a serious cancer that affects kids, to find new ways to help treat young patients with this condition.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-11019687

• How metabolic signals affect the function of immune cells involved in cancer and autoimmune diseases

  This study is looking at how the way Treg cells use energy affects their ability to help or hinder the immune system, which is important for people with cancer or autoimmune diseases, and the goal is to find better treatments that could improve immunotherapy and manage these conditions.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-10998984

• Understanding how sickle cell disease affects blood stem cells

  This study is looking at how sickle cell disease affects the blood-forming stem cells and their support system in the bone marrow, focusing on how certain cells change and what that means for people with sickle cell disease.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-10923842

• Investigating how cancer-associated fibroblasts affect tumor growth in pediatric neuroblastoma

  This study is looking at how certain cells in tumors, called cancer-associated fibroblasts, affect the growth of neuroblastoma in kids, with the hope that understanding these interactions can help improve treatment and outcomes for young patients.

  NIH research St. Jude Children's Research Hospital Graduate School of Biomedical Sciences, LLC · Memphis, United States · NIH-10912574

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