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Clinical trials and research at Krystal Biotech, Inc.

• 9Clinical trials
• 1Country

Newest trials

All recruiting trials (9)

• Topical KB111 for Hailey-Hailey Disease (early phase, kids and adults)

  This study tests whether a topical KB111 treatment is safe and helps with lesions in people with Hailey-Hailey disease, including adolescents and adults.

  Recruiting Early Phase 1 Krystal Biotech, Inc. · Miami, Florida · NCT07717346

• KB803 eye drops versus placebo for people with dystrophic epidermolysis bullosa

  This trial tests whether KB803 eye drops, given three times a week, can reduce recurrent corneal abrasions in children and adults with dystrophic epidermolysis bullosa.

  Recruiting at 5 sites Phase 3 Krystal Biotech, Inc. · Rancho Santa Margarita, California and 4 other locations · NCT07016750

• KB801 versus placebo for healing corneal defects in stage 2 or 3 neurotrophic keratitis

  This tests whether KB801 eye drops can safely heal persistent corneal epithelial defects in adults with stage 2 or 3 neurotrophic keratitis.

  Recruiting at 7 sites Phase 1/2 Krystal Biotech, Inc. · Irvine, California and 8 other locations · NCT06999733

• Observing corneal abrasions in patients with Dystrophic Epidermolysis Bullosa

  This study looks at how corneal abrasions develop over time in people with Dystrophic Epidermolysis Bullosa by tracking their symptoms through weekly diaries and monthly questionnaires.

  Recruiting Krystal Biotech, Inc. · Pittsburgh, Pennsylvania · NCT06563414

• Treatment of advanced lung cancer using KB707

  This study is testing a new treatment called KB707 to see if it can help adults with advanced lung cancer by boosting their immune response, especially for those who haven't had success with standard therapies.

  Recruiting at 10 sites Phase 1/2 Krystal Biotech, Inc. · Dothan, Alabama and 13 other locations · NCT06228326

• Treatment of Alpha-1 Antitrypsin Deficiency with KB408

  This study is testing a new treatment called KB408 to see if it can help adults with alpha-1 antitrypsin deficiency breathe better by delivering a key protein directly to their lungs.

  Recruiting at 3 sites Phase 1 Krystal Biotech, Inc. · Gainesville, Florida and 2 other locations · NCT06049082

• Assessing KB707 for treating advanced melanoma and solid tumors

  This study is testing a new treatment called KB707, which is a modified virus, to see if it can help adults with advanced melanoma and other solid tumors who haven't had success with regular treatments.

  Recruiting at 15 sites Phase 1/2 Krystal Biotech, Inc. · Los Angeles, California and 14 other locations · NCT05970497

• Assessing KB407 for treating cystic fibrosis

  This study is testing a new inhaled treatment called KB407 to see if it is safe and how well it works for adults with cystic fibrosis.

  Recruiting at 6 sites Phase 1 Krystal Biotech, Inc. · Gainesville, Florida and 5 other locations · NCT05504837

• Long-term follow-up for gene therapy in skin conditions

  This study is checking the long-term safety of a gene therapy for people with a skin condition called dystrophic epidermolysis bullosa who have already received the treatment.

  Recruiting at 3 sites Krystal Biotech, Inc. · Rancho Santa Margarita, California and 2 other locations · NCT04917887

Quick answers

How many clinical trials run by Krystal Biotech, Inc. are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 1: 2, Phase 3: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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