Sponsor or institution
Clinical trials and research at Boston University Medical Campus
As of November 12, 2026, Find a Trial lists 639 NIH-funded research projects at this institution, with $462.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 639NIH research projects
NIH-funded research (newest 40 of 639)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Creating a detailed map of early lung cancer changes
This study is looking at early changes in lung tissue that can lead to cancer, specifically focusing on common types of lung cancer, and it's for patients who want to help researchers understand these changes better so they can improve early detection and treatment.
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Telomere trouble in ALT cancers: what causes damage and how it happens
Researchers are studying why some cancer cells use ALT to lengthen telomeres and how replication stress damages telomeres, aiming to uncover key processes that could be targeted in patients.
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IL-6 signaling, lung injury, and post-TB lung disease in TB/HIV
This grant tests how a specific immune signal (IL-6) relates to lung damage after tuberculosis in people with and without HIV, aiming to understand who is at risk for lasting lung problems.
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IL-6 signaling and lung injury after TB and HIV co-infection
This project looks at how a common immune signal called IL-6 relates to lung injury after TB treatment, especially in people who also have HIV.
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LEAD Africa: advancing Alzheimer’s research across Africa
A new project aims to build Alzheimer’s disease research capabilities in Africa to improve understanding and care for people with dementia.
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Leading AD and related dementias research in Africa
A multi-country effort aims to build Africa’s capacity to study Alzheimer’s disease and related dementias using scalable, low-cost methods.
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Alzheimer’s disease research collaboration in Africa to build precision medicine resources
A multi-country project in Africa and the U.S. aims to create accessible, scalable ways to study Alzheimer’s disease and related dementias using new data and local infrastructure.
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Genetic clues to Alzheimer's disease in Jewish and Arab communities
This grant studies how genes influence Alzheimer's risk in Jews from the Middle East–North Africa and related groups to uncover variants that may affect disease in diverse populations.
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Genetic clues to Alzheimer's in Jewish and Arab communities
This project looks for genetic factors linked to Alzheimer’s disease in Jews from Israel and Arabs living in the region to understand why some people are at higher risk.
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Genetic clues for Alzheimer’s in Jewish and Arab communities
Researchers will study genetic factors linked to Alzheimer’s disease in Jewish and Arab populations to uncover variants that may influence risk.
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CKDu in Central American agricultural communities
A research effort is studying a kidney disease affecting younger farm workers in El Salvador and Nicaragua to understand its causes and how it progresses.
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Integrating U=U into HIV counseling to boost viral suppression
A large study in South Africa uses a patient-friendly counseling app called Undetectable & You to help people understand that undetectable HIV means no transmission and to improve ART adherence.
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New insights into how G proteins are regulated and how this affects brain signaling
A NIH-funded project looks at a new class of brain proteins that control cell signaling, aiming to understand how this affects memory, aging, and Alzheimer’s-related changes.
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Testing and texting in dental clinics to fight HIV
Aimed at making HIV prevention easier by testing patients in dental offices and exploring the use of a long-acting injectable PrEP in dental settings.
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How lung immune cells develop and metabolize to fight tuberculosis
This project looks at how lung immune cells called alveolar macrophages behave and use energy to influence tuberculosis infection, with the goal of guiding better vaccines and therapies.
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Single-cell view of lung macrophage roles in TB lesions
A short, patient-friendly look at how different lung macrophages influence tuberculosis outcomes and lesion growth at the infection site.
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CKDu in Central American farm communities: understanding kidney disease in El Salvador and Nicaragua
A human-focused research project aims to understand why younger agricultural workers in Central America are getting kidney disease and what can be done to prevent it.
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CAFE: A Coordinating Center to Unite and Grow Health and Extreme Weather Research
A nationwide team is building a shared hub to connect researchers, manage data, and provide training so health and extreme weather research can move faster and reach more people.
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CKDu in Central American agricultural communities
A nationwide effort to understand why chronic kidney disease is killing many working-age people in El Salvador and Nicaragua, especially farm workers.
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Next steps for PTSD genomics: from loci to function
A study from Boston University Medical Campus aims to identify genetic factors and brain-cell changes linked to PTSD to help develop better biomarkers and treatments for people with PTSD.
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Neutrophils and vascular aging in large blood vessels
A patient-facing look at how certain immune cells (neutrophils) may drive stiffness and damage in aging arteries, potentially influencing heart and brain health.
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Why COVID caused less illness in Malawi
This project looks at how past infections like malaria, worm infections, nutrition, and other health factors change immune responses to COVID-19 in adults in Malawi.
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Why COVID caused less severe illness in Malawi
This project looks at whether past infections like malaria and parasitic worms change adults' immune responses and affect how COVID infections and vaccine protection work in Malawi.
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Neutrophil and nerve interactions in painful dental pulp inflammation
This grant studies how neutrophils and sensory nerves interact to drive pain in pulpitis, with a focus on potentially better, less invasive ways to manage dental pain.
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Influenza and SARS-CoV-2 in pregnancy in India
A study following pregnant women in India to track how flu and COVID viruses affect mothers and newborns.
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Global Network for Women's and Children's Health: improving care before, during, and after birth
A collaborative program to test affordable, scalable health interventions for mothers and young children in India and other sites to reduce illness and death.
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Can speaking Native languages and English protect memory in American Indian older adults?
This project looks at whether speaking both Native languages and English helps lower the risk of memory loss and dementia in American Indian older adults.
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GLP-1 medicines to improve heart, kidney, and metabolic health for people with HIV and type 2 diabetes
A real-world study will look at how GLP-1 receptor agonists affect heart and kidney health and lifetime costs for people living with HIV and type 2 diabetes.
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Understanding sudden unexpected infant deaths in Zambia and nearby African countries
This project looks at how often sudden unexpected deaths happen in infants in Zambia and nearby African countries and which common, changeable factors may increase the risk.
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Prefrontal-cingulate brain networks and aging in humans
Researchers are studying how aging affects brain networks in the frontal areas to help understand age-related memory and thinking changes in adults.
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Understanding age-related tauopathies that contribute to Alzheimer's disease
This project studies how different age-related brain diseases with abnormal tau protein relate to and help cause Alzheimer’s disease.
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CD31, APOE, and CRP: a pathway linked to Alzheimer's disease in people
A study at Boston University Medical Campus will explore how a blood protein (CRP) and APOE variants interact with a specific brain blood vessel receptor (CD31) to influence inflammation and Alzheimer’s disease in humans.
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Heat and pregnancy: how hot Weather Affects Placental Health and Birth
A study following pregnant people to understand how exposure to heat during pregnancy may impact placental health and birth outcomes.
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Role of Schwann Cell Precursors in Fracture Healing
This NIH grant explores how a specific nerve-support cell type called Schwann cell precursors may influence bone healing and pain after fractures, using mouse models to map how these cells behave during healing.
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Endocrine-disrupting chemicals and infertility risk in Black women
This grant studies how environmental chemicals in the blood and urine may affect how long women take to conceive, focusing on African American women.
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Down Syndrome and Alzheimer’s: Understanding Health Trajectories and Care Using Medicaid Data
This project uses large health data to understand how Alzheimer’s dementia develops and affects adults with Down syndrome, with the goal of guiding better care and planning.
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Public health messages about blunt use harms for young adults
New public health messages will explain the harms of smoking blunts to help young adults reduce or quit blunt use.
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Study of C5aR receptors in mice to understand immune signaling
A small grant will create a special mouse line to study how C5a receptors control immune responses in inflammation.
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Lung-specific factors that drive TB progression
This NIH grant looks at how lung cells and the lung environment influence tuberculosis progression in adults and how this could lead to better prevention and treatments.
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Thin Filaments and Muscle Regulation in Heart and Skeletal Muscle
Researchers are studying how the tiny structures that control muscle contraction work, and how mutations can disrupt them, which could help people with heart or muscle diseases.
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