Can speaking Native languages and English protect memory in American Indian older adults?

Bilingualism as a protective factor of ADRD in American Indian adults: the Strong Heart Study

NIH-funded research Boston University Medical Campus · NIH-11471312

This project looks at whether speaking both Native languages and English helps lower the risk of memory loss and dementia in American Indian older adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11471312 on NIH RePORTER

What this research studies

You would see how lifelong language use relates to thinking and memory by using data from American Indian adults in the Strong Heart Study. The team combines language-history questions, cognitive tests, and health and social information to link bilingual experience with brain health. They will account for things like age, sex, education, past boarding-school experiences, physical and mental health, and social activity so results are fair and relevant. The goal is to improve how we measure and support brain health in American Indian communities.

Who could benefit from this research

Good fit: Ideal participants are American Indian adults in the Strong Heart Study cohort, especially older adults (around age 65 and up) who can report their language history and complete cognitive testing.

Not a fit: People who are not American Indian or who do not speak multiple languages may not find the results directly applicable to their own dementia risk.

Why it matters

Potential benefit: If successful, this work could identify language-related strengths that help protect memory and guide culturally tailored dementia prevention for American Indian communities.

How similar studies have performed: Other research has reported mixed evidence that bilingualism supports cognitive reserve, but studies in American Indian communities are limited, so this project addresses an understudied gap.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.