Sponsor or institution
Clinical trials and research at Auburn University at Auburn
As of November 12, 2026, Find a Trial lists 67 NIH-funded research projects at this institution, with $23.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 67NIH research projects
NIH-funded research (newest 40 of 67)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Hierarchical molecular test kit to detect and quantify C. difficile and C. perfringens in animal feed and livestock
A new, layered molecular panel helps detect and precisely measure harmful bacteria in animal feed and livestock to protect veterinary health and food safety.
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DNA sequencing tool to improve veterinary bacterial diagnostics
Auburn University plans to buy a DNA sequencing instrument to quickly and accurately identify bacteria in animals and animal-related samples.
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Advancing Pan-RAS Inhibitors to Prevent Colorectal Cancer
Researchers are testing a new pan-RAS drug candidate to prevent colorectal cancer development in preclinical models, with the goal of stopping tumor growth before it starts.
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Good Nights Sleep for Kids and Parents
A randomized trial at a US university to help families with 0-11 year olds sleep better by improving sleep habits and the sleep environment, especially in low-income households.
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Rewilding Immunology: How Diverse Mice Predict Human Immune Responses to Vaccines
A scientist team at Auburn University will study how genetically diverse mice respond to nanoparticle-based vaccines to better predict what might happen in people.
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Could brain inflammation cause loss of pleasure and motivation?
Looks at whether blood and brain inflammation are tied to reduced pleasure and motivation in teens and adults.
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Multimodal brain and body signals linked to binge drinking in the lab and real life
Researchers are studying how brain activity, stress hormones, and immune signals relate to cravings and drinking in young adults who binge drink, both in the lab and in everyday life.
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Machine learning enhanced nanoplasmonic biosensing for immune profiling
Auburn University researchers are developing a fast, point-of-care test that uses machine learning and advanced biosensors to map a patient’s immune signals, helping diagnose and monitor immune-related illnesses like autoimmune diseases and cancer.
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Portable ion mobility device to speed up diagnosis of multiple diseases (including Alzheimer's)
A small, field-ready device using advanced ion mobility technology to quickly identify disease biomarkers in patient samples, potentially helping early and accurate diagnoses.
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Reducing minority stress to help sexual minority adults with eating disorders
This project tests a new, identity-affirming treatment approach designed to help sexual minority adults with eating disorders by addressing stigma-related stress and coping skills.
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FDA Vet-LIRN veterinary testing capacity for animal food-related illnesses
A program to boost animal health testing capacity at university labs to quickly identify and respond to animal food-borne illnesses and related outbreaks.
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Engineered Colon Cancer Tissue in Obese Environments
Aims to study how obesity-related changes in the tumor environment influence colorectal cancer using patient-derived, lab-made colon cancer models.
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Pan-RAS Inhibitors from Natural Products to Stop Colorectal Cancer Early
A research team will screen natural product libraries to find compounds that block mutant RAS activity in early colorectal cancer, with the goal of preventing progression.
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Oogenesis and Speciation: How Environment Shapes Reproductive Barriers
A study at Auburn University will look at how environmental stress affects female gamete development (oogenesis) and, in turn, how it may drive the formation of new species and relate to infertility concerns.
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Cell movement and stress in tissues: how physical forces shape cancer and aging
Researchers are studying how the physical environment and pressure within tissues influence how cells move, survive, and communicate, with a focus on cancer and aging.
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Synthesis of partially saturated nitrogen rings through selective dearomatization of heteroarenes
A new chemical method aims to make partially saturated nitrogen-containing rings more efficiently, which could benefit drug, crop, and material science applications.
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How alcohol harms the gut's cell-cleanup process and affects liver health
This project looks at how heavy drinking disrupts the gut’s cell-cleaning system (autophagy) and how that contributes to alcohol-related liver disease, aiming to point to new treatment targets for people with ALD.
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Sleep and health disparities: how sleep shapes outcomes from adolescence into young adulthood
This project follows teens and young adults in Alabama to see how sleep problems relate to health, stress, and wellbeing over several years, especially across different socioeconomic backgrounds.
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AU403, a new drug that targets brain receptors linked to Alzheimer's disease
Researchers aim to find out if a new medicine called AU403 that activates specific brain receptors (LXRβ and PPARγ) can reduce Alzheimer’s-related brain changes in people with Alzheimer's disease.
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Combining patient groups to find cancer risk patterns and reduce disparities
This project uses data from many different groups of cancer patients to build better tools that predict who is at higher risk and who might avoid unnecessary treatments.
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Personalized pathway profiles to find cancer subtypes and predict outcomes
This project is building personalized pathway-based profiles from multiple types of tumor data to find subtypes and improve prognosis for people with breast and other cancers.
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Keeping reductions in self-injury and aggression for people with intellectual and developmental disabilities
This project tries a behavioral approach to help people with intellectual and developmental disabilities keep improvements in self-injury and aggressive behavior after treatment ends.
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Improving rewards to reduce self-injury and aggression in people with developmental disabilities
Looks at how changing the type, timing, and amount of rewards can help people with intellectual and developmental disabilities lower self-injury and aggression.
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A Portable Device for Diagnosing Many Diseases
This research aims to create a small, portable device that can quickly and accurately identify signs of various diseases in people.
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AI-powered blood biosensors for precise immune monitoring
This project builds fast, AI-enhanced blood tests to read immune signals for people with autoimmune disease, cancer, infection, allergy, or transplant concerns.
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Understanding Colon Cancer Growth in Obese Patients
This project explores how obesity affects the growth and behavior of colon cancer cells to find new ways to help patients.
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Understanding How Egg Development Affects Fertility
This project explores how environmental stress impacts egg development, which could help us understand why some people experience infertility.
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A new medicine for lung cancer caused by specific gene changes
Scientists are working to create a new medicine that targets a specific gene change called RAS, which often causes lung cancer.
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Understanding how cells move in diseases like cancer and heart conditions
This project explores how cells move and react to their environment, hoping to find new ways to prevent and treat diseases like cancer, heart problems, and issues related to aging.
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Improving biomedical research with advanced mass spectrometry equipment
This study is all about getting a new, advanced machine to help scientists at Auburn University do better research on health and medicine, so they can find new ways to improve treatments and outcomes for patients.
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Understanding how stress affects cannabis use motivation in people with cannabis use disorder
This study is looking at how stress affects the desire to use cannabis in people who struggle with cannabis use disorder, and it aims to find out how stress changes brain activity when they see things related to cannabis, which could help develop better treatments.
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Investigating the role of ERBB4 in certain types of melanoma
This study is looking at how changes in the ERBB4 gene might help certain skin cancers grow, and it's for people with a type of melanoma that doesn't have good treatment options right now; the goal is to find new ways to help improve their care.
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Addressing opioid misuse and disparities in treatment access in the Deep South
This study is looking into how to help people in the Deep South who are struggling with opioid misuse, especially older adults, racial and ethnic minorities, and LGBTQ+ individuals, by finding out what makes it hard for them to get the treatment and support they need.
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Understanding how lysosome damage contributes to liver disease from alcohol use
This study is looking at how drinking alcohol affects liver cells, especially how it damages tiny structures called lysosomes, which can lead to liver problems; the goal is to find new ways to treat or prevent alcohol-related liver disease.
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Testing a new treatment for Alzheimer's disease
This study is testing a new treatment called AU403 for Alzheimer's disease to see if it can help improve symptoms or slow down the disease, and it's designed for people living with Alzheimer's who are looking for new options.
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Investigating how discrimination affects sleep in Black Americans
This study is looking at how experiences of discrimination affect sleep quality for Black Americans, and it invites participants to share their daily feelings and experiences while also tracking their sleep patterns to better understand this connection.
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Creating a device to measure properties of respiratory and drug particles in real-time
This study is working on a new device that can measure tiny particles in the air and droplets to help us understand how respiratory viruses spread and how well medications can reach the lungs, making it easier to improve treatments for everyone.
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Using multi-omics data to improve cancer subtype discovery and prognosis
This study is looking at how genes work together in cancer to create personalized profiles for patients, which could help doctors find the best treatments for each individual.
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Creating tools to predict immune responses based on individual differences
This study is working on new computer tools to help understand how our immune system spots germs, which could lead to better vaccines and treatments for allergies and cancer, taking into account that everyone’s body is a little different.
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Improving emotional coping skills for people with cannabis use disorder
This study is testing a quick online program designed to help people with Cannabis Use Disorder learn to handle tough emotions better, and it includes helpful text reminders to keep you on track; by joining, you'll see if this approach can help you use less cannabis and feel more in control of your feelings.
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